Trial reportGait & posture2017
Long-term effects of lateral wedge orthotics on hip and ankle joint space widths.
Trial report in Gait & posture, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00076453 (Clinical Effects of Altered Biomechanics in Knee Osteoarthritis), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Effects of Altered Biomechanics in Knee Osteoarthritis
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Pain-Related Impairment and Talar Tilt as Predictors of Surgical Decision Making in Advanced Varus Ankle Osteoarthritis.Foot & ankle orthopaedics · 2026Article
- Overview of Ankle Arthropathy in Hereditary Hemochromatosis.Medical sciences (Basel, Switzerland) · 2023Review
- Walking with Different Insoles Changes Lower-Limb Biomechanics Globally in Patients with Medial Knee Osteoarthritis.Journal of clinical medicine · 2023Article
- Ankle osteoarthritis: comprehensive review and treatment algorithm proposal.EFORT open reviews · 2022Review
- Ankle Osteoarthritis.Revista brasileira de ortopedia · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLateral wedge insoles have been used for the treatment of medial knee osteoarthritis (OA) and have been shown to reduce loading of the medial compartment of the knee. However, as the entire lower extremity acts as a single kinetic chain, altering the biomechanics of the knee may also have significant effects at the ankles or hips. We aimed to evaluate the effects of lateral wedge orthotics on ankle and hip joints, compared to neutral orthotics, by assessing the changes in joint space width (JSW) during 36 months of continuous use.
methodsWe prospectively enrolled 109 subjects with symptomatic osteoarthritis of the medial knee according to the American College of Rheumatology criteria. The trial was double blind and patients were randomized to either wedged or neutral orthotic shoe inserts. Hip and ankle JSWs were quantified using plain radiographies at baseline and at 36-months follow-up.
findings45 patients completed the 36 month study. 31 of those who completed the study were using the lateral wedge versus 14 were using neutral orthotics. 2 patients in the wedge group had missing radiographs and were not included in the JSW analyses. There were no significant differences between the wedge and the neutral orthotics groups in the magnitude of JSW change at either the hip or the ankles at 36 month.
interpretationWe found no significant adverse effects of the lateral wedges on ankles or hips. (ClinicalTrials.gov NCT00076453).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.