Evidence map›Paper›PMID 27693864›Full record

ArticleProtist2016

Acanthamoeba and Dictyostelium Use Different Foraging Strategies.

Nick A Kuburich, Nirakar Adhikari, Jeffrey A Hadwiger

Open access · greenAbstract read
In one paragraph

Article in Protist, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Long-term culturing ofApplied and environmental microbiology · 2025
    Article
  4. Article
  5. Chemokinesis by a microbial predator.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Continuous Real-Time Motility Analysis ofPathogens (Basel, Switzerland) · 2021
    Article
  10. The Ecology and Evolution of Amoeba-Bacterium Interactions.Applied and environmental microbiology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nick A Kuburich *Department of Microbiology and Molecular Genetics, Oklahoma State University, 307 Life Sciences East, Stillwater, OK 74078-3020, USA.
Nirakar Adhikari *Department of Microbiology and Molecular Genetics, Oklahoma State University, 307 Life Sciences East, Stillwater, OK 74078-3020, USA.
Jeffrey A HadwigerDepartment of Microbiology and Molecular Genetics, Oklahoma State University, 307 Life Sciences East, Stillwater, OK 74078-3020, USA.
Oklahoma State University · US

Funding

Role of STAT proteins in MAPK signal transduction pathwaysR15GM097717 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI HADWIGER, JEFFREY A · 2011 to 2011
$276k
NIGMS NIH HHS R15 GM097717
6 · The paper itself

Abstract

Amoeba often use cell movement as a mechanism to find food, such as bacteria, in their environment. The chemotactic movement of the soil amoeba Dictyostelium to folate or other pterin compounds released by bacteria is a well-documented foraging mechanism. Acanthamoeba can also feed on bacteria but relatively little is known about the mechanism(s) by which this amoeba locates bacteria. Acanthamoeba movement in the presence of folate or bacteria was analyzed in above agar assays and compared to that observed for Dictyostelium. The overall mobility of Acanthamoeba was robust like that of Dictyostelium but Acanthamoeba did not display a chemotactic response to folate. In the presence of bacteria, Acanthamoeba only showed a marginal bias in directed movement whereas Dictyostelium displayed a strong chemotactic response. A comparison of genomes revealed that Acanthamoeba and Dictyostelium share some similarities in G protein signaling components but that specific G proteins used in Dictyostelium chemotactic responses were not present in current Acanthamoeba genome sequence data. The results of this study suggest that Acanthamoeba does not use chemotaxis as the primary mechanism to find bacterial food sources and that the chemotactic responses of Dictyostelium to bacteria may have co-evolved with chemotactic responses that facilitate multicellular development.

Indexed as

ChemotaxisAcanthamoebaDictyosteliumPhylogenyProtozoan ProteinsSignal TransductionProtozoan ProteinsAcanthamoebaChemotaxisDictyosteliumG proteins

Identifiers

PMID27693864
PMCPMC5154823
OpenAlexW2516151746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.