Evidence map›Paper›PMID 27693721›Full record

ArticleJournal of molecular biology2016

Nucleobases Undergo Dynamic Rearrangements during RNA Tertiary Folding.

Robb Welty, Kathleen B Hall

Abstract read
In one paragraph

Article in Journal of molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Perspective - RNA Dynamics Today and Tomorrow.Journal of molecular biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robb WeltyDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: robb@wustl.edu.
Kathleen B HallDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: kathleenhal@gmail.com.

Funding

RNA-ligand interactions: simulation and experimentR01GM098102 · NIGMS · WASHINGTON UNIVERSITY · PI CHEATHAM, THOMAS E., HALL, KATHLEEN B · 2011 to 2014
$2.1M
NIGMS NIH HHS R01 GM098102
6 · The paper itself

Abstract

The tertiary structure of the GTPase center (GAC) of 23S ribosomal RNA (rRNA) as seen in cocrystals is extremely compact. It is stabilized by long-range hydrogen bonds and nucleobase stacking and by a triloop that forms within its three-way junction. Its folding pathway from secondary structure to tertiary structure has not been previously observed, but it was shown to require Mg

Indexed as

Nucleic Acid ConformationRNA FoldingCations, DivalentKineticsMagnesiumRNA, Ribosomal, 23SCations, DivalentMagnesiumRNA, Ribosomal, 23S2-aminopurine fluorescenceGTPase center RNARNA folding kineticsstopped-flow fluorescence

Identifiers

PMID27693721
PMCPMC5085838

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.