Evidence map›Paper›PMID 27693650›Full record

ArticleJournal of molecular biology2016

MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded β-Barrel Monomers with a Ca

Luana G M Ferrara, Gregor D Wallat, Lucile Moynié, Naresh N Dhanasekar, Soumeya Aliouane, Silvia Acosta-Gutiérrez, Jean-Marie Pagès, Jean-Michel Bolla, Mathias Winterhalter, Matteo Ceccarelli and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. The Ion Permeability of DNA Nanotube Channels.Small (Weinheim an der Bergstrasse, Germany) · 2026
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  5. mBio · 2025
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  10. Article
  11. Article
  12. Article
  13. Ferric quinate (QPLEX) interacts with the major outer membrane protein (MOMP) ofComputational and structural biotechnology journal · 2022
    Article
  14. RevisitingFrontiers in cellular and infection microbiology · 2020
    Review
  15. Membrane Proteocomplexome ofFrontiers in microbiology · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 5 countries.

Luana G M FerraraBiomedical Sciences Research Complex, University of St Andrews, 09042 St Andrews, UK.
Gregor D WallatBiomedical Sciences Research Complex, University of St Andrews, 09042 St Andrews, UK.
Lucile MoyniéBiomedical Sciences Research Complex, University of St Andrews, 09042 St Andrews, UK.
Naresh N DhanasekarDepartment of Life Sciences and Chemistry, Jacobs University Bremen, 28719 Bremen, Germany.
Soumeya AliouaneAix Marseille Univ, IRBA, TMCD2, 13385 Marseille, France.
Silvia Acosta-GutiérrezDepartment of Physics, University of Cagliari, Cittadella Universitaria Monserrato, S.P8-km 0.700, 09042 Monserrato, Cagliari (CA), Italy.
Jean-Marie PagèsAix Marseille Univ, IRBA, TMCD2, 13385 Marseille, France.
Jean-Michel BollaAix Marseille Univ, IRBA, TMCD2, 13385 Marseille, France.
Mathias WinterhalterDepartment of Life Sciences and Chemistry, Jacobs University Bremen, 28719 Bremen, Germany.
Matteo CeccarelliDepartment of Physics, University of Cagliari, Cittadella Universitaria Monserrato, S.P8-km 0.700, 09042 Monserrato, Cagliari (CA), Italy.
James H NaismithBiomedical Sciences Research Complex, University of St Andrews, 09042 St Andrews, UK; State Key Laboratory of Biotherapy, Sichuan University, Chengdu 610041, China. Electronic address: naismith@st-andrews.ac.uk.
Aix-Marseille Université · FRUniversity of St Andrews · GBConstructor University · DEUniversity of Cagliari · ITSichuan University · CN

Funding

Wellcome Trust WT100209MA
6 · The paper itself

Abstract

The Gram-negative organism Campylobacter jejuni is the major cause of food poisoning. Unlike Escherichia coli, which has two major porins, OmpC and OmpF, C. jejuni has one, termed major outer membrane protein (MOMP) through which nutrients and antibiotics transit. We report the 2.1-Å crystal structure of C. jejuni MOMP expressed in E. coli and a lower resolution but otherwise identical structure purified directly from C. jejuni. The 2.1-Å resolution structure of recombinant MOMP showed that although the protein has timeric arrangement similar to OmpC, it is an 18-stranded, not 16-stranded, β-barrel. The structure has identified a Ca

Indexed as

Anti-Bacterial AgentsBacterial ProteinsCalciumCampylobacter jejuniCiprofloxacinCrystallography, X-RayEscherichia coliGene ExpressionModels, MolecularMultiprotein ComplexesPorinsProtein ConformationRecombinant ProteinsAnti-Bacterial AgentsBacterial ProteinsCalciumCiprofloxacinmajor outer membrane protein, Campylobacter jejuniMultiprotein ComplexesPorinsRecombinant Proteinsantibiotic resistanceCampylobacterouter membrane proteinsporinsβ-barrel

Identifiers

PMID27693650
PMCPMC5090048
OpenAlexW2527543780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.