Evidence map›Paper›PMID 27693420›Full record

Trial reportArchives of physical medicine and rehabilitation2017

Association Between 6-Minute Walk Test Distance and Objective Variables of Functional Capacity After Exercise Training in Elderly Heart Failure Patients With Preserved Ejection Fraction: A Randomized Exercise Trial.

Sara Maldonado-Martín, Peter H Brubaker, Joel Eggebeen, Kathryn P Stewart, Dalane W Kitzman

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Archives of physical medicine and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05349786 (The Effect of the Physical Activity Program on Quality of Life, Functional Capacity and Mortality Risk Level in Individuals With Heart Failure), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05349786 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effect of the Physical Activity Program on Quality of Life, Functional Capacity and Mortality Risk Level in Individuals With Heart Failure

TypeinterventionalSponsorNigde Omer Halisdemir UniversityRan2018 to 2021Enrolled40ConditionsHeart Failure, Nursing CariesArmsPhysical activity program
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sara Maldonado-MartínDepartment of Physical Education and Sport, Faculty of Education and Sport-Physical Activity and Sport Section, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, Araba/Álava, Basque Country, Spain. Electronic address: sara.maldonado@ehu.eus.
Peter H BrubakerDepartment of Health and Exercise Science, Wake Forest School of Medicine, Winston-Salem, NC.
Joel EggebeenSections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest University, Winston-Salem, NC.
Kathryn P StewartSections on Cardiovascular Medicine and Geriatrics, Department of Internal Medicine, Wake Forest University, Winston-Salem, NC.
Dalane W KitzmanDepartment of Health and Exercise Science, Wake Forest School of Medicine, Winston-Salem, NC.
Wake Forest University · USUniversity of the Basque Country · ES

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
REHAB-HF: A Trial of Rehabilitation Therapy in Older Acute Heart Failure PatientsR01AG045551 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2014 to 2018
$6.8M
Exercise Intolerance in Older HFPEF PatientsR01AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2001 to 2019
$5.2M
Loss of fat tissue and functional responses to exercise in older, obese adultsR01AG020583 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J · 2002 to 2013
$4.0M
Exercise Intolerance in Elderly Diastolic Heart FailureR37AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2005 to 2013
$3.4M
Effect of fat loss on functional and cardiovascular benefits of aerobic exerciseR01HL093713 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J · 2009 to 2013
$3.4M
NHLBI NIH HHS R01 HL093713NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG018915NIA NIH HHS R01 AG020583NIA NIH HHS R01 AG045551NIA NIH HHS R37 AG018915
6 · The paper itself

Abstract

objectiveTo evaluate the change in the 6-minute walk test (6-MWT) distance relative to changes in key functional capacity measures after 16 weeks of exercise training in older patients (≥65y) who have heart failure with preserved ejection fraction (HFpEF).

designProspective, randomized, single-blinded (by researchers to patient group) comparison of 2 groups of HFpEF patients.

settingHospital and clinic records; ambulatory outpatients.

participantsParticipants (N=47) randomly assigned to an attention control (AC) (n=24) or exercise training (ET) (n=23) group.

interventionThe ET group performed cycling and walking at 50% to 70% of peak oxygen uptake (V˙o

main outcome measuresV˙o

resultsAt follow-up, the 6-MWT distance was higher than at the baseline in both the ET (11%, P=.005) and AC (9%, P=.004) groups. In contrast, V˙o

conclusionsThe results of this study challenge the validity of using the 6-MWT as a serial measure of exercise tolerance in elderly HFpEF patients and suggest that submaximal and peak exercise should be determined objectively by VT and V˙o

Indexed as

Exercise TherapyExercise ToleranceFemaleHeart FailureHumansMaleOxygen ConsumptionProspective StudiesSingle-Blind MethodWalk TestExercise testOxygen consumptionPhysical fitnessRehabilitation

Identifiers

PMID27693420
PMCPMC7707852
OpenAlexW2526698715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.