ArticleCurrent biology : CB2016
Rats Remember Items in Context Using Episodic Memory.
Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed.
- Rats replay episodic memories in context.Current biology : CB · 2026Article
- Short-term plasticity influences episodic memory recall: an interplay of synaptic traces in a spiking neural network model.Scientific reports · 2025Article
- Validation of a rodent model of episodic memory replay.Learning & behavior · 2025Article
- Tell me why: the missing w in episodic memory's what, where, and when.Cognitive, affective & behavioral neuroscience · 2025Review
- Mental time travel in the rat.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The function of episodic memory in animals.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Review
- Mice integrate conspecific and contextual information in forming social episodic-like memories under spontaneous recognition task conditions.Scientific reports · 2024Article
- Neuroglycome alterations of hippocampus and prefrontal cortex of juvenile rats chronically exposed to glyphosate-based herbicide.Frontiers in neuroscience · 2024Article
- Impaired episodic-like memory in a mouse model of Alzheimer's disease is associated with hyperactivity in prefrontal-hippocampal regions.Disease models & mechanisms · 2023Article
- Olfactory neurogenesis and its role in fear memory modulation.Frontiers in behavioral neuroscience · 2023Review
- Memory recall: New behavioral protocols for examining distinct forms of context specific recall in animals.Neurobiology of learning and memory · 2022Article
- Episodic-like memory is preserved with age in cuttlefish.Proceedings. Biological sciences · 2021Article
- What can we teach Lymnaea and what can Lymnaea teach us?Biological reviews of the Cambridge Philosophical Society · 2021Review
- Episodic-like memory of rats as retrospective retrieval of incidentally encoded locations and involvement of the retrosplenial cortex.Scientific reports · 2021Article
- Translation-Focused Approaches to GPCR Drug Discovery for Cognitive Impairments Associated with Schizophrenia.ACS pharmacology & translational science · 2020Review
- The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties.Neuroscience and biobehavioral reviews · 2020Review
- Article
- Crossing the Rubicon: Behaviorism, Language, and Evolutionary Continuity.Frontiers in psychology · 2020Review
- Biological Sex and Sex Hormone Impacts on Deficits in Episodic-Like Memory in a Rat Model of Early, Pre-motor Stages of Parkinson's Disease.Frontiers in neurology · 2020Article
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Abstract
Vivid episodic memories in people have been characterized as the replay of unique events in sequential order [1-3]. Animal models of episodic memory have successfully documented episodic memory of a single event (e.g., [4-8]). However, a fundamental feature of episodic memory in people is that it involves multiple events, and notably, episodic memory impairments in human diseases are not limited to a single event. Critically, it is not known whether animals remember many unique events using episodic memory. Here, we show that rats remember many unique events and the contexts in which the events occurred using episodic memory. We used an olfactory memory assessment in which new (but not old) odors were rewarded using 32 items. Rats were presented with 16 odors in one context and the same odors in a second context. To attain high accuracy, the rats needed to remember item in context because each odor was rewarded as a new item in each context. The demands on item-in-context memory were varied by assessing memory with 2, 3, 5, or 15 unpredictable transitions between contexts, and item-in-context memory survived a 45 min retention interval challenge. When the memory of item in context was put in conflict with non-episodic familiarity cues, rats relied on item in context using episodic memory. Our findings suggest that rats remember multiple unique events and the contexts in which these events occurred using episodic memory and support the view that rats may be used to model fundamental aspects of human cognition.
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