Evidence map›Paper›PMID 27692973›Full record

ReviewSleep medicine reviews2017

Waking up is the hardest thing I do all day: Sleep inertia and sleep drunkenness.

Lynn M Trotti

Abstract readReview
In one paragraph

Review in Sleep medicine reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 213 citations in OpenAlex.

  1. Trial
  2. Trial
  3. A minimal clinically important difference for the sleep inertia visual analog scale in idiopathic hypersomnia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Anchoring and Sleep Inertia.Experimental psychology · 2022
    Trial
  8. Article
  9. Boundary-Dependent Sleep-Wake Dysregulation in Idiopathic Hypersomnia.Annals of clinical and translational neurology · 2026
    Article
  10. Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  11. Article
  12. Association between sleep inertia and cognitive performance among older adults in the Wisconsin Sleep Cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. Clinical and polysomnographic changes in idiopathic hypersomnia ten years after the diagnosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  17. Article
  18. Idiopathic hypersomnia is a 24-hour disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
  19. Article
  20. Article

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lynn M TrottiEmory Sleep Center and Department of Neurology, Emory University School of Medicine, 12 Executive Park Dr NE, Atlanta, GA 30329, USA. Electronic address: Lbecke2@emory.edu.
Emory University · US

Funding

Sleepiness and sleep drunkenness: narcolepsy versus GABA-related hypersomniaK23NS083748 · NINDS · EMORY UNIVERSITY · PI TROTTI, LYNN MARIE · 2014 to 2018
$918k
NINDS NIH HHS K23 NS083748
6 · The paper itself

Abstract

The transition from sleep to wake is marked by sleep inertia, a distinct state that is measurably different from wakefulness and manifests as performance impairments and sleepiness. Although the precise substrate of sleep inertia is unknown, electroencephalographic, evoked potential, and neuroimaging studies suggest the persistence of some features of sleep beyond the point of awakening. Forced desynchrony studies have demonstrated that sleep inertia impacts cognition differently than do homeostatic and circadian drives and that sleep inertia is most intense during awakenings from the biological night. Recovery sleep after sleep deprivation also amplifies sleep inertia, although the effects of deep sleep vary based on task and timing. In patients with hypersomnolence disorders, especially but not exclusively idiopathic hypersomnia, a more pronounced period of confusion and sleepiness upon awakening, known as "sleep drunkenness", is common and problematic. Optimal treatment of sleep drunkenness is unknown, although several medications have been used with benefit in small case series. Difficulty with awakening is also commonly endorsed by individuals with mood disorders, disproportionately to the general population. This may represent an important treatment target, but evidence-based treatment guidance is not yet available.

Indexed as

HumansParasomniasSleepIdiopathic hypersomniaMood disordersNarcolepsySleep drunkennessSleep inertia

Identifiers

PMID27692973
PMCPMC5337178
OpenAlexW2511381041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.