Evidence map›Paper›PMID 27692792›Full record

ArticleAmerican journal of surgery2017

Incidence, characteristics, and management of recently diagnosed, microscopically invasive breast cancer by receptor status: Iowa SEER 2000 to 2013.

Alexandra Thomas, Ronald J Weigel, Charles F Lynch, Philip M Spanheimer, Elizabeth K Breitbach, Mary C Schroeder

Abstract read
In one paragraph

Article in American journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Repression of miR-135b-5p promotes metastasis of early-stage breast cancer by regulating downstream target SDCBP.Laboratory investigation; a journal of technical methods and pathology · 2019
    Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandra ThomasDivision of Hematology, Oncology and Blood and Marrow Transplantation, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Ronald J WeigelDepartment of Surgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Charles F LynchDepartment of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA.
Philip M SpanheimerDepartment of Surgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Elizabeth K BreitbachCarver College of Medicine, University of Iowa, Iowa City, IA, USA.
Mary C SchroederDivision of Health Services Research, Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, IA, USA. Electronic address: mary-schroeder@uiowa.edu.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
NCI NIH HHS HHSN261201000032CNCI NIH HHS P30 CA086862
6 · The paper itself

Abstract

backgroundRecent incidence, treatment patterns, and outcomes for node negative microscopically invasive breast cancer (MIBC) have not been reported.

methodsState Health Registry of Iowa data identified women with ductal carcinoma in situ (DCIS), MIBC, and stage I breast cancer excluding MIBC (stage 1BC).

resultsFrom 2000 to 2013, 1,706, 193, and 4,514 women were diagnosed with DCIS, MIBC, and stage 1BC, respectively. MIBC increased at an annual percentage change of 2.1 (P = .041). MIBC was more frequently human epidermal growth factor receptor 2 positive than stage 1BC (39.7% vs 9.6%, P < .001). Mastectomy was performed more frequently in MIBC than DCIS (40.9% vs 30.6%, P = .014) or stage 1BC (40.9% vs 33.8%, P = .119). Chemotherapy was given to 4.1% of women with MIBC. Survival for women with MIBC was intermediate between DCIS and stage 1BC.

conclusionsManagement of MIBC is an increasingly frequent clinical scenario. Women with MIBC receive more aggressive local and systemic therapy than women with DCIS.

Indexed as

Breast NeoplasmsCarcinoma, Intraductal, NoninfiltratingErb-b2 Receptor Tyrosine KinasesFemaleHumansIncidenceIowaMiddle AgedNeoplasm InvasivenessNeoplasm StagingSEER ProgramERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesBreast neoplasmsCancer incidenceMastectomyMicroinvasive tumorSEER program

Identifiers

PMID27692792
PMCPMC5334458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.