Evidence map›Paper›PMID 27692611›Full record

ArticleImmunity2016

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1

Salvador Iborra, María Martínez-López, Sofía C Khouili, Michel Enamorado, Francisco J Cueto, Ruth Conde-Garrosa, Carlos Del Fresno, David Sancho

Open access · bronzeAbstract read
In one paragraph

Article in Immunity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 152 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 1 synthesis or guideline pooled it, 208 citations in OpenAlex.

  1. Tissue-Resident Memory T Cells in Skin Diseases: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
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  10. Origins of CD8 tissue resident memory.Frontiers in immunology · 2026
    Review
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Salvador IborraCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain. Electronic address: siborra@cnic.es.
María Martínez-LópezCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain.
Sofía C KhouiliCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain.
Michel EnamoradoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain.
Francisco J CuetoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain; Department of Biochemistry, Faculty of Medicine, Universidad Autónoma de Madrid, Calle Arzobispo Morcillo 4, Madrid, 28029, Spain.
Ruth Conde-GarrosaCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain.
Carlos Del FresnoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain.
David SanchoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, Madrid, 28029, Spain. Electronic address: dsancho@cnic.es.
Spanish National Centre for Cardiovascular Research · ESUniversidad Autónoma de Madrid · ES

Funding

European Research Council 260414NIAID NIH HHS HHSN272201300006C
6 · The paper itself

Abstract

Despite the crucial role of tissue-resident memory T (Trm) cells in protective immunity, their priming remains poorly understood. Here, we have shown differential priming requirements for Trm versus circulating memory CD8

Indexed as

AnimalsCD24 AntigenCD8-Positive T-LymphocytesCross-PrimingDendritic CellsImmunologic MemoryInterleukin-12Interleukin-15Lectins, C-TypeLymph NodesMiceMice, Inbred C57BLMice, TransgenicReceptors, ImmunologicSkinVacciniaCD24 AntigenClec9a protein, mouseInterleukin-12Interleukin-15Lectins, C-TypeReceptors, Immunologic

Identifiers

PMID27692611
PMCPMC5074364
OpenAlexW2526605295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.