ArticleeLife2016
The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones.
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Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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0cells of the map it votes in
45citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
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Who cites it
45 citing papers in PubMed, 65 citations in OpenAlex.
- CAF-1 in Replication and Repair: A Critical Genetic Mediator of Synthesis-Coupled Nucleosome Assembly.Biomolecules · 2026Review
- Newly synthesized histones: passive or active players in the regulation of epigenetic inheritance?Nucleic acids research · 2026Review
- Chromatin Assembly Factor 1 is required for normal structure and function of facultative heterochromatin inbioRxiv : the preprint server for biology · 2026Article
- Insights into the synchronization between DNA replication and parental histone recycling.Biochemical Society transactions · 2025Review
- Stepwise order in protein complex assembly: approaches and emerging themes.Open biology · 2025Review
- Replication-coupled inheritance of chromatin states.Cell insight · 2024Review
- Structure of the Hir histone chaperone complex.Molecular cell · 2024Article
- Acute multi-level response to defectivebioRxiv : the preprint server for biology · 2024Article
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- Article
- CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands.Nucleic acids research · 2023Article
- The Role of Histone Modification in DNA Replication-Coupled Nucleosome Assembly and Cancer.International journal of molecular sciences · 2023Review
- The Histone Chaperone Network Is Highly Conserved inInternational journal of molecular sciences · 2023Article
- Mechanisms of chromatin-based epigenetic inheritance.Science China. Life sciences · 2022Review
- Unorthodox PCNA Binding by Chromatin Assembly Factor 1.International journal of molecular sciences · 2022Article
- Managing the Steady State Chromatin Landscape by Nucleosome Dynamics.Annual review of biochemistry · 2022Review
- Biochemical and Structural Insights into the Winged Helix Domain of P150, the Largest Subunit of the Chromatin Assembly Factor 1.International journal of molecular sciences · 2022Article
- Histones and their chaperones: Adaptive remodelers of an ever-changing chromatinic landscape.Frontiers in genetics · 2022Review
- Histone variants in skeletal myogenesis.Epigenetics · 2021Review
- Cac1 WHD and PIP domains have distinct roles in replisome progression and genomic stability.Current genetics · 2021Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Wallace H LiuDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, United States.
Sarah C RoemerDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, United States.
Yeyun ZhouDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, United States.
Zih-Jie ShenDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, United States.
Briana K DenneheyDepartment of Epigenetics and Molecular Carcinogenesis, MD Anderson Cancer Center, Houston, United States.
Jeremy L BalsbaughDepartment of Chemistry and Biochemistry, University of Colorado, Boulder, Boulder, United States.
Jennifer C LiddleDepartment of Chemistry and Biochemistry, University of Colorado, Boulder, Boulder, United States.
Travis NemkovProgram in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, United States.
Natalie G AhnDepartment of Chemistry and Biochemistry, University of Colorado, Boulder, Boulder, United States.
Kirk C HansenProgram in Structural Biology and Biochemistry, University of Colorado School of Medicine, Aurora, United States.
Jessica K TylerDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, United States.ORCID http://orcid.org/0000-0001-9765-1659
Mair Ea ChurchillDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, United States.ORCID http://orcid.org/0000-0003-0862-235X
University of Colorado Denver · USUniversity of Colorado Boulder · USThe University of Texas MD Anderson Cancer Center · USCornell University · US
Funding
University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0MColorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0MTRAINING IN SIGNAL TRANSDUCTION &CELL CYCLE REGULATIONT32GM008759 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI AHN, NATALIE G. · 2000 to 2020
$5.9MPredoctoral Training Program in Signaling and Cellular Regulation INCLUDE Down Syndrome SupplementT32GM142607 · NIGMS · UNIVERSITY OF COLORADO · PI Sabrina Leigh Spencer, Tin Tin Su · 2021 to 2026
$3.6MLinking Dynamics to Catalysis and Inhibition in ERK2R01GM114594 · NIGMS · UNIVERSITY OF COLORADO · PI AHN, NATALIE G. · 2016 to 2019
$1.3MStructural and Functional Studies of the Histone Chaperone CAF-1R01GM111902 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI CHURCHILL, MAIR E · 2014 to 2017
$1.2MQuantum 315 r DetectorS10OD012073 · OD · MOLECULAR BIOLOGY CONSORTIUM · PI NIX, JAY C. · 2012 to 2012
$600kLTQ Orbitrap Mass Spectrometer RequestS10RR024599 · NCRR · UNIVERSITY OF COLORADO DENVER · PI HANSEN, KIRK C · 2009 to 2009
$500kABI Elite ESI-QqTOF Mass Spectrometry SystemS10RR026641 · NCRR · UNIVERSITY OF COLORADO · PI AHN, NATALIE G. · 2010 to 2010
$458kMacromolecular X-ray Data Collection InstrumentationS10OD012033 · OD · UNIVERSITY OF COLORADO DENVER · PI CHURCHILL, MAIR E · 2014 to 2014
$421kNCATS NIH HHS UL1 TR001082NCI NIH HHS P30 CA046934NCRR NIH HHS S10 RR024599NCRR NIH HHS S10 RR026641NIGMS NIH HHS R01 GM111902NIGMS NIH HHS R01 GM114594NIGMS NIH HHS T32 GM008759NIGMS NIH HHS T32 GM142607NIH HHS S10 OD012033NIH HHS S10 OD012073
Abstract
The histone chaperone Chromatin Assembly Factor 1 (CAF-1) deposits tetrameric (H3/H4)
Indexed as
biophysicschromosomesgeneshistone chaperonehistonesmass spectrometryNucleosomeprotein-protein interactionsS. cerevisiaestructural biology
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.