ArticleInternational journal of molecular sciences2016
Cinnamide Derivatives as Mammalian Arginase Inhibitors: Synthesis, Biological Evaluation and Molecular Docking.
Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Caffeic Acid Phenethyl Ester (CAPE) Inhibits Arginase Activity and Growth ofPathogens (Basel, Switzerland) · 2025Article
- Synthesis of Arginase Inhibitors: An Overview.Pharmaceutics · 2025Review
- Therapeutic potential of natural arginase modulators: mechanisms, challenges, and future directions.Frontiers in pharmacology · 2025Review
- A colorimetric assay adapted to fragment screening revealing aurones and chalcones as new arginase inhibitors.RSC medicinal chemistry · 2024Article
- Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes.Journal of natural medicines · 2023Article
- Towards Arginase Inhibition: Hybrid SAR Protocol for Property Mapping of ChlorinatedInternational journal of molecular sciences · 2023Article
- Inhibiting Human andTropical medicine and infectious disease · 2022Article
- In Vitro and In Silico Analyses of New Cinnamid and Rosmarinic Acid-Derived Compounds Biosynthesized inPathogens (Basel, Switzerland) · 2022Article
- Virtual Screening for FDA-Approved Drugs That Selectively Inhibit Arginase Type 1 and 2.Molecules (Basel, Switzerland) · 2022Article
- Natural Products That Target the Arginase inMicroorganisms · 2021Review
- Cinnamides TargetMolecules (Basel, Switzerland) · 2020Article
- Arginase as a Potential Biomarker of Disease Progression: A Molecular Imaging Perspective.International journal of molecular sciences · 2020Review
- Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors.RSC medicinal chemistry · 2020Article
- Roles of eNOS in atherosclerosis treatment.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arginases are enzymes that are involved in many human diseases and have been targeted for new treatments. Here a series of cinnamides was designed, synthesized and evaluated in vitro and in silico for their inhibitory activity against mammalian arginase. Using a microassay on purified liver bovine arginase (b-ARG I), (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.