Evidence map›Paper›PMID 27689992›Full record

ArticleInternational journal of molecular sciences2016

Urine Levels of Defensin α1 Reflect Kidney Injury in Leptospirosis Patients.

Haorile Chagan-Yasutan, Yue Chen, Talitha Lea Lacuesta, Prisca Susan A Leano, Hiroko Iwasaki, Firmanto Hanan, Delsi Taurustiati, Yasukazu Ohmoto, Yugo Ashino, Hiroki Saitoh and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Kidney Injury Biomarkers in Leptospirosis.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Review
  2. Review
  3. Article
  4. Kidney biomarkers in tropical infections: an update.Pathogens and global health · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Haorile Chagan-YasutanDisaster-Related Infectious Disease, International Research Institute of Disaster Science, Tohoku University, 980-8575 Sendai, Japan. haorile@gmail.com.
Yue ChenEmerging Infectious Diseases, Department of Internal Medicine, Graduate School of Medicine, Tohoku University, 980-8575 Sendai, Japan. chenyue69@hotmail.com.
Talitha Lea LacuestaAdult Infectious Disease and Tropical Medicine Department, San Lazaro Hospital, 1003 Manila, Philippines. talea211md@yahoo.com.
Prisca Susan A LeanoNational Reference Laboratory for HIV/AIDS, Hepatitis, and other STDs, STD/AIDS Cooperative Central Laboratory, 1003 Manila, Philippines. s_leano@yahoo.com.
Hiroko IwasakiDisaster-Related Infectious Disease, International Research Institute of Disaster Science, Tohoku University, 980-8575 Sendai, Japan. hiwasaki@irides.tohoku.ac.jp.
Firmanto HananEmerging Infectious Diseases, Department of Internal Medicine, Graduate School of Medicine, Tohoku University, 980-8575 Sendai, Japan. 009fireman@gmail.com.
Delsi TaurustiatiEmerging Infectious Diseases, Department of Internal Medicine, Graduate School of Medicine, Tohoku University, 980-8575 Sendai, Japan. tdelsi@yahoo.co.id.
Yasukazu OhmotoResearch Institute of Pharmacological Therapeutical Development, Otsuka Pharmaceutical Co., Ltd., 771-0192 Tokushima, Japan. ohmoto.yasukazu@otsuka.jp.
Yugo AshinoDisaster-Related Infectious Disease, International Research Institute of Disaster Science, Tohoku University, 980-8575 Sendai, Japan. ya82@yahoo.co.jp.
Hiroki SaitohEmerging Infectious Diseases, Department of Internal Medicine, Graduate School of Medicine, Tohoku University, 980-8575 Sendai, Japan. hsaitoh9813135@med.tohoku.ac.jp.
Hideyasu KiyomotoDivision of Integrated Nephrology and Telemedicine, Tohoku Medical Megabank Organization, Tohoku University, 980-8573 Sendai, Japan. kiyo@med.tohoku.ac.jp.
Yasuhiko SuzukiResearch Center for Zoonosis Control, Hokkaido University, 001-0020 Sapporo, Japan. suzuki@czc.hokudai.ac.jp.
Freda O Elizabeth TelanNational Reference Laboratory for HIV/AIDS, Hepatitis, and other STDs, STD/AIDS Cooperative Central Laboratory, 1003 Manila, Philippines. betelan@yahoo.com.
Toshio HattoriDisaster-Related Infectious Disease, International Research Institute of Disaster Science, Tohoku University, 980-8575 Sendai, Japan. toshatto@med.tohoku.ac.jp.
Tohoku University · JPHokkaido University · JPOtsuka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is a zoonotic disease whose severe forms are often accompanied by kidney dysfunction. In the present study, urinary markers were studied for potential prediction of disease severity. Urine samples from 135 patients with or without leptospirosis at San Lazaro Hospital, the Philippines, were analyzed. Urine levels of defensin α1 (uDA1) were compared with those of neutrophil gelatinase-associated lipocalin (uNGAL) and

Indexed as

defensin α1">d-glucosidase (NAG)kidney injuryleptospirosisN-acetyl-β-neutrophil gelatinase-associated lipocalin (NGAL)

Identifiers

PMID27689992
PMCPMC5085670
OpenAlexW2527401160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.