Evidence map›Paper›PMID 27689688›Full record

Trial reportNutrition and cancer

A Randomized Controlled Trial to Increase Navy Bean or Rice Bran Consumption in Colorectal Cancer Survivors.

Erica C Borresen, Dustin G Brown, Greg Harbison, Lynn Taylor, Amanda Fairbanks, Joanne O'Malia, Marlon Bazan, Sangeeta Rao, Susan M Bailey, Melissa Wdowik and 3 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition and cancer. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01929122 (BENEFIT), which is not on this map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01929122 nacompletednot on this map

BENEFIT: Beans/Bran Enriching Nutritional Eating For Intestinal Health Trial

TypeinterventionalSponsorColorado State UniversityRan2010 to 2014Enrolled29ConditionsColorectal Cancer Control and PreventionArmsPlacebo-Control Meals and Snacks, Cooked Navy Bean Powder Meals and Snacks, Rice Bran Meals and Snacks
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Do Common Beans (Nutrients · 2021
    Pooled it
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  6. Pooled it
  7. Trial
  8. Trial
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  11. Trial
  12. Article
  13. Article
  14. Article
  15. Role ofPlants (Basel, Switzerland) · 2022
    Review
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  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Erica C Borresena Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Dustin G Browna Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Greg Harbisona Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Lynn Taylora Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Amanda Fairbanksa Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Joanne O'Maliab University of Colorado Health-North Cancer Clinical Research , Fort Collins , Colorado , USA.
Marlon Bazanb University of Colorado Health-North Cancer Clinical Research , Fort Collins , Colorado , USA.
Sangeeta Raoc Department of Clinical Sciences , Colorado State University , Fort Collins , Colorado , USA.
Susan M Baileya Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Melissa Wdowikd Department of Food Science and Human Nutrition , Colorado State University , Fort Collins , Colorado , USA.
Tiffany L Weird Department of Food Science and Human Nutrition , Colorado State University , Fort Collins , Colorado , USA.
Regina J Brownf University of Colorado School of Medicine , Aurora , Colorado , USA.
Elizabeth P Ryana Department of Environmental and Radiological Health Sciences , Colorado State University , Fort Collins , Colorado , USA.
Colorado State University · USUniversity of Colorado Health · USUniversity of Colorado Cancer Center · USUniversity of Colorado Denver · US

Funding

Dietary Rice Bran Phytochemicals and Microbial Metabolites for Colon ChemopreventR21CA161472 · NCI · COLORADO STATE UNIVERSITY · PI RYAN, ELIZABETH P, WEIR, TIFFANY L · 2012 to 2013
$339k
NCI NIH HHS R21 CA161472
6 · The paper itself

Abstract

Consumption of navy beans (NB) and rice bran (RB) have been shown to inhibit colon carcinogenesis. Given the overall poor diet quality in colorectal cancer (CRC) survivors and low reported intake of whole grains and legumes, practical strategies to increase consumption merit attention. This study determined feasibility of increasing NB or RB intake in CRC survivors to increase dietary fiber and examined serum inflammatory biomarkers and telomere lengths. Twenty-nine subjects completed a randomized controlled trial with foods that included cooked NB powder (35 g/day), heat-stabilized RB (30 g/day), or no additional ingredient. Fasting blood, food logs, and gastrointestinal health questionnaires were collected. The amount of NB or RB consumed equated to 4-9% of subjects' daily caloric intake and no major gastrointestinal issues were reported with increased consumption. Dietary fiber amounts increased in NB and RB groups at Weeks 2 and 4 compared to baseline and to control (P ≤ 0.01). Telomere length correlated with age and HDL cholesterol at baseline, and with improved serum amyloid A (SAA) levels at Week 4 (P ≤ 0.05). This study concludes feasibility of increased dietary NB and RB consumption to levels associated with CRC chemoprevention and warrants longer-term investigations with both foods in high-risk populations that include cancer prevention and control outcomes.

Indexed as

OryzaPhaseolusAgedBiomarkersCancer SurvivorsCholesterol, HDLColorectal NeoplasmsDietary FiberDietary SupplementsFemaleHumansInflammationMaleMiddle AgedSerum Amyloid A ProteinTelomere HomeostasisBiomarkersCholesterol, HDLDietary FiberSerum Amyloid A Protein

Identifiers

PMID27689688
PMCPMC5145262
OpenAlexW2526052248

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.