ArticleJournal of renal injury prevention2016
The effects of different electrolyte composition in dialysate on QTc interval; a controlled trial.
Article in Journal of renal injury prevention, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- The Effect of Dialysate Bicarbonate Concentration or Oral Bicarbonate Supplementation on Outcomes in Patients on Maintenance Dialysis: A Systematic Review and Meta-Analysis.Canadian journal of kidney health and disease · 2025Article
- Article
- Effect of Hemodialysis on Corrected QT Interval and QTc Dispersion.Indian journal of nephrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHemodialysis (HD) has impact on the cardiovascular system by inducing changes in the characteristics of body fluids such as PH, temperature and electrolyte concentrations. In the previous studies, prolongation of the QT interval and increase of QT dispersion have been reported during HD sessions. These changes were more significant while using solutions with less potassium and higher bicarbonate during dialysis.
objectivesThe aim of our study was to investigate the effects of different potassium and bicarbonate concentrations on electrocardiography (ECG) parameters and the electrochemical balance of cell membranes. PATIENTS AND
methodsThis is a double blind controlled clinical trial with crossover design. This interventional study has been conducted on 36 patients over 18 years who undergoing HD 3 times a week for at least 6 months. Twelve-lead ECG has been obtained before starting and one hour after end of each HD session. The QTc was measured and changes recorded by a cardiologist. Correlations were evaluated by univariate regression analysis.
results54.38 years (16 to 77 years), 66.7% were male. No significant increase in QT interval has been seen while dialyzing with 2 meq/l potassium and 24 meq/l bicarbonate, 2 meq/l potassium and 28 meq/l bicarbonate and 3 meq/l potassium and 24 meq/l bicarbonate beside high calcium (2.5 meq/l) dialysate was conducted. Age, gender, serum calcium and serum bicarbonate level before HD session did not influence the mean QT intervals before and after dialysis.
conclusionConcentration of potassium beside moderate dose of bicarbonate in dialysis bath had not any significant influence on QT intervals after dialysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.