Evidence map›Paper›PMID 27689039›Full record

ArticleClinical and experimental reproductive medicine2016

Clinical outcomes of single versus double blastocyst transfer in fresh and vitrified-warmed cycles.

Jin Hee Eum, Jae Kyun Park, So Young Kim, Soo Kyung Paek, Hyun Ha Seok, Eun Mi Chang, Dong Ryul Lee, Woo Sik Lee

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental reproductive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Extended culture of poor-quality supernumerary embryos improves ART outcomes.Journal of assisted reproduction and genetics · 2018
    Article
  6. [Pregnancy and obstetric outcomes of elective single versus double cleavage-stage embryo transfer].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2016
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jin Hee EumFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
Jae Kyun ParkFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
So Young KimFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
Soo Kyung PaekFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
Hyun Ha SeokFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
Eun Mi ChangFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
Dong Ryul LeeFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.; Department of Biomedical Science, College of Life Science, CHA University, Seoul, Korea.
Woo Sik LeeFertility Center of CHA Gangnam Medical Center, College of Medicine, CHA University, Seoul, Korea.
CHA University · KRCHA University Gangnam Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAssisted reproductive technology has been associated with an increase in multiple pregnancies. The most effective strategy for reducing multiple pregnancies is single embryo transfer. Beginning in October 2015, the National Supporting Program for Infertility in South Korea has limited the number of embryos that can be transferred per in vitro fertilization (IVF) cycle depending on the patient's age. However, little is known regarding the effect of age and number of transferred embryos on the clinical outcomes of Korean patients. Thus, this study was performed to evaluate the effect of the number of transferred blastocysts on clinical outcomes.

methodsThis study was carried out in the Fertility Center of CHA Gangnam Medical Center from January 2013 to December 2014. The clinical outcomes of 514 women who underwent the transfer of one or two blastocysts on day 5 after IVF and of 721 women who underwent the transfer of one or two vitrified-warmed blastocysts were analyzed retrospectively.

resultsFor both fresh and vitrified-warmed cycles, the clinical pregnancy rate and live birth or ongoing pregnancy rate were not significantly different between patients who underwent elective single blastocyst transfer (eSBT) and patients who underwent double blastocyst transfer (DBT), regardless of age. However, the multiple pregnancy rate was significantly lower in the eSBT group than in the DBT group.

conclusionThe clinical outcomes of eSBT and DBT were equivalent, but eSBT had a lower risk of multiple pregnancy and is, therefore, the best option.

Indexed as

Blastocyst transferIn vitro fertilizationLive birth pregnancy rateMultiple pregnancySingle embryo transfer

Identifiers

PMID27689039
PMCPMC5039309
OpenAlexW2524874937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.