ArticleBrain and behavior2016
Reliable measurements of brain atrophy in individual patients with multiple sclerosis.
Article in Brain and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Commercial volumetric MRI reporting tools in multiple sclerosis: a systematic review of the evidence.Neuroradiology · 2023Pooled it
- Technical and clinical validation of commercial automated volumetric MRI tools for dementia diagnosis-a systematic review.Neuroradiology · 2021Pooled it
- Clinical and Paraclinical Biomarkers and the Hitches to Assess Conversion to Secondary Progressive Multiple Sclerosis: A Systematic Review.Frontiers in neurology · 2021Pooled it
- Translating research findings into clinical practice: a systematic and critical review of neuroimaging-based clinical tools for brain disorders.Translational psychiatry · 2020Pooled it
- Automated Segmentation of Tissues Using CT and MRI: A Systematic Review.Academic radiology · 2019Pooled it
- The current state of demographic subgroup reporting for commercially available AI for radiology: a scoping review.European radiology · 2026Article
- Comparison of Three Automated Measurements of Ventricular Volumes of the Brain.Journal of imaging informatics in medicine · 2026Article
- ENIGMA's advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions.MethodsX · 2025Article
- Relation of Visual Function, Retinal Thickness by Optical Coherence Tomography, and MRI Brain Volume in Pediatric-Onset Multiple Sclerosis.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Optical Coherence Tomography Angiography Is Associated with Disease Activity Expressed by NEDA-3 Status in Patients with Relapsing Multiple Sclerosis.Journal of clinical medicine · 2025Article
- Real-world brain volumetry in multiple sclerosis: importance of methodological consistency and clinical relevance of gray matter atrophy.Frontiers in neurology · 2025Article
- Relationship between brain atrophy and disability in a multi-site multiple sclerosis registry.BMJ neurology open · 2025Article
- RECLAIM-A retrospective, multicenter observational study aimed at enabling the development of artificial intelligence-driven prognostic models for disease progression in multiple sclerosis.Frontiers in neurology · 2025Article
- A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023Article
- The Vessel Has Been Recanalized: Now What?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Longitudinal changes in global structural brain connectivity and cognitive performance in former hospitalized COVID-19 survivors: an exploratory study.Experimental brain research · 2023Article
- Recent Progress in the Identification of Early Transition Biomarkers from Relapsing-Remitting to Progressive Multiple Sclerosis.International journal of molecular sciences · 2023Review
- Learning from pseudo-labels: deep networks improve consistency in longitudinal brain volume estimation.Frontiers in neuroscience · 2023Article
- Quantification of amyloid PET for future clinical use: a state-of-the-art review.European journal of nuclear medicine and molecular imaging · 2022Review
- Validation of an automatic tool for the rapid measurement of brain atrophy and white matter hyperintensity: QyScore®.European radiology · 2022Article
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAs neurodegeneration is recognized as a major contributor to disability in multiple sclerosis (MS), brain atrophy quantification could have a high added value in clinical practice to assess treatment efficacy and disease progression, provided that it has a sufficiently low measurement error to draw meaningful conclusions for an individual patient.
methodIn this paper, we present an automated longitudinal method based on Jacobian integration for measuring whole-brain and gray matter atrophy based on anatomical magnetic resonance images (MRI), named MS
resultsMS
conclusionTherefore, we can conclude that MS
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.