Evidence map›Paper›PMID 27688890›Full record

ReviewHorticulture research2016

Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plants.

Joshua R Widhalm, David Rhodes

Abstract readReview
In one paragraph

Review in Horticulture research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
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  5. Review
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  14. MeJA-induced hairy roots inFrontiers in plant science · 2024
    Article
  15. Article
  16. Article
  17. Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2023
    Review
  18. Review
  19. Cellular Stress-Induced Metabolites inJournal of natural products · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joshua R WidhalmDepartment of Horticulture and Landscape Architecture, Purdue University, 625 Agriculture Mall Drive , West Lafayette, IN 47907-2010, USA.ORCID 0000-0002-2703-4740
David RhodesDepartment of Horticulture and Landscape Architecture, Purdue University, 625 Agriculture Mall Drive , West Lafayette, IN 47907-2010, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 1,4-naphthoquinones (1,4-NQs) are a diverse group of natural products found in every kingdom of life. Plants, including many horticultural species, collectively synthesize hundreds of specialized 1,4-NQs with ecological roles in plant-plant (allelopathy), plant-insect and plant-microbe interactions. Numerous horticultural plants producing 1,4-NQs have also served as sources of traditional medicines for hundreds of years. As a result, horticultural species have been at the forefront of many basic studies conducted to understand the metabolism and function of specialized plant 1,4-NQs. Several 1,4-NQ natural products derived from horticultural plants have also emerged as promising scaffolds for developing new drugs. In this review, the current understanding of the core metabolic pathways leading to plant 1,4-NQs is provided with additional emphasis on downstream natural products originating from horticultural species. An overview on the biochemical mechanisms of action, both from an ecological and pharmacological perspective, of 1,4-NQs derived from horticultural plants is also provided. In addition, future directions for improving basic knowledge about plant 1,4-NQ metabolism are discussed.

Identifiers

PMID27688890
PMCPMC5030760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.