Evidence map›Paper›PMID 27688873›Full record

ArticleIsrael journal of health policy research2016

The cost and value of cancer drugs - are new innovations outpacing our ability to pay?

Daniel A Goldstein, Salomon M Stemmer, Noa Gordon

Abstract readEditorial
In one paragraph

Article in Israel journal of health policy research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Repurposing metformin as a potential anticancer agent using in silico technique.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Article
  4. Article
  5. Direct Medical Costs of Advanced Breast Cancer Treatment: A Real-World Study in the Southeast of The Netherlands.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2021
    Article
  6. Article
  7. The insurability of innovative pharmaceutical cancer technologies.Israel journal of health policy research · 2020
    Article
  8. Article
  9. Review
  10. Do patient access schemes for high-cost cancer drugs deliver value to society?-lessons from the NHS Cancer Drugs Fund.Annals of oncology : official journal of the European Society for Medical Oncology · 2017
    Review
  11. The IJHPR celebrates five years of quality publication.Israel journal of health policy research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel A GoldsteinDavidoff Cancer Center, Rabin Medical Center, Petach Tikvah, Israel ; Winship Cancer Institute, Emory University, Atlanta, GA USA.
Salomon M StemmerDavidoff Cancer Center, Rabin Medical Center, Petach Tikvah, Israel ; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Noa GordonDavidoff Cancer Center, Rabin Medical Center, Petach Tikvah, Israel ; Ben Gurion University of the Negev, Beer Sheva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer drug expenditures have been increasing significantly in countries around the world. A recent paper in the IJHPR provides new knowledge and insights into this global phenomenon by analyzing how it is playing out in an Israeli health plan with over two million members, whose state-of-the-art information systems provide an opportunity to explore these changes in a comprehensive, detailed and reliable manner. There is a wide variation in both the cost-effectiveness and the budget impact of individual drugs. These issues also vary when analyzing drugs in other countries due to differential pricing mechanisms. In addition to drug expenditure, the overall cost of cancer care is increasing, partly due to expenditures on non-pharmacologic treatments and diagnostic testing. With the arrival of new therapies, the future of cancer care is exciting. However, there will be many challenges ahead with regard to the ability to pay for such innovations. In this commentary we discuss the current problems and anticipate the future challenges.

Identifiers

PMID27688873
PMCPMC5032240

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.