Evidence map›Paper›PMID 27688793›Full record

ArticleAIDS research and therapy

Nutritional status and its effect on treatment outcome among HIV infected clients receiving HAART in Ethiopia: a cohort study.

Sadikalmahdi Hussen, Tefera Belachew, Nezif Hussien

Open access · goldAbstract read
In one paragraph

Article in AIDS research and therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sadikalmahdi HussenClinical Pharmacy Department, School of Pharmacy, Jimma University, Jimma, Ethiopia.
Tefera BelachewHuman Nutrition Department, Jimma University, Jimma, Ethiopia.
Nezif HussienClinical Pharmacy Department, School of Pharmacy, Jimma University, Jimma, Ethiopia.
Jimma University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposesThe aim of this study was to determine the effects of nutritional status at the start of highly active anti-retroviral therapy on treatment outcomes among HIV/AIDS patients taking HAART at Jimma University Specialized Hospital.

methodsWe performed a retrospective cohort study involving 340 adults who started highly active anti-retroviral therapy. The patients have been clinically followed for 2 years. Data were extracted from paper based medical charts by trained data collectors from January 30 to February 28, 2014 using data collection format. We entered data into Epi data version 3.1 and then exported to SPSS for windows version 21. Predictors of CD4 change were identified using multivariable linear regression model. Time to an event (death) was estimated by Kaplan-Meier and predictors of mortality were identified by Cox proportional hazard model.

resultsOut of 340 patients, 42 patients died during the follow-up. Twenty-five (59.5 %) deaths were from malnourished group. Age, baseline CD4, sex, baseline HAART and marital status were significant predictors of immunologic recovery at different time points. Malnutrition was associated with lower CD4 recovery and greater hazard of death.

conclusionsMalnutrition tends to decrease CD4 recovery and predisposes patient to early death.

Indexed as

CD4DeathEthiopiaMalnutritionSurvival

Identifiers

PMID27688793
PMCPMC5034514
OpenAlexW2521155120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.