ArticleEvidence-based complementary and alternative medicine : eCAM2016
Acupuncture Decreases Blood Pressure Related to Hypothalamus Functional Connectivity with Frontal Lobe, Cerebellum, and Insula: A Study of Instantaneous and Short-Term Acupuncture Treatment in Essential Hypertension.
Article in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Effects and Mechanisms of Acupuncture on Diarrhea-Predominant Irritable Bowel Syndrome: A Systematic Review.Frontiers in neuroscience · 2022Pooled it
- Efficacy and Safety of Acupuncture for Essential Hypertension: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2018Pooled it
- Review
- Clinical study of acupuncture combined with surface anesthesia using proparacaine in geriatric cataract phacoemulsification.World journal of clinical cases · 2023Article
- A functional connectome signature of blood pressure in >30 000 participants from the UK biobank.Cardiovascular research · 2023Article
- Acupuncture with twirling reinforcing and reducing manipulation shows a control of hypertension and regulation of blood pressure-related target brain regions in spontaneously hypertensive rat: a preliminary resting-state functional MRI study.Frontiers in neuroscience · 2023Article
- Electroacupuncture and manual acupuncture at LR3 and ST36 have attenuating effects on hypertension and subsequent cognitive dysfunction in spontaneously hypertensive rats: A preliminary resting-state functional magnetic resonance imaging study.Frontiers in neuroscience · 2023Article
- Resting-State fMRI in Studies of Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Acupuncture Attenuates Blood Pressure via Inducing the Expression of nNOS.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Progress of Acupuncture Therapy in Diseases Based on Magnetic Resonance Image Studies: A Literature Review.Frontiers in human neuroscience · 2021Review
- Frequency-Specific Blood Oxygen Level Dependent Oscillations Associated With Pain Relief From Ankle Acupuncture in Patients With Chronic Low Back Pain.Frontiers in neuroscience · 2021Article
- The Hypotensive Role of Acupuncture in Hypertension: Clinical Study and Mechanistic Study.Frontiers in aging neuroscience · 2020Review
- Perioperative acupuncture medicine: a novel concept instead of acupuncture anesthesia.Chinese medical journal · 2019Review
- The Mechanism of Acupuncture in Treating Essential Hypertension: A Narrative Review.International journal of hypertension · 2019Review
- Different Brain Activation after Acupuncture at Combined Acupoints and Single Acupoint in Hypertension Patients: An Rs-fMRI Study Based on ReHo Analysis.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Can Acupuncture Treatment of Hypertension Improve Brain Health? A Mini Review.Frontiers in aging neuroscience · 2019Article
- Effect of Acupuncture at LR3 on Cerebral Glucose Metabolism in a Rat Model of Hypertension: AEvidence-based complementary and alternative medicine : eCAM · 2018Article
- A Study of Traditional Chinese Medicine Body Constitution Associated with Overweight, Obesity, and Underweight.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- The role of insula-cerebellum connection underlying aversive regulation with acupuncture.Molecular painArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The therapeutic effects of acupuncture in decreasing blood pressure are ambiguous and underlying acupuncture in hypertension treatment has not been investigated. Our objective was to observe the change of quality of life and compare the differences in brain functional connectivity by investigating instantaneous and short-term acupuncture treatment in essential hypertension patients. A total of 30 patients were randomly divided into the LR3 group and sham acupoint group. Subjects received resting-state fMRI among preacupuncture, postinstantaneous, and short-term acupuncture treatment in two groups. Hypothalamus was selected as the seed point to analyze the changes in connectivity. We found three kinds of results: (1) There was statistical difference in systolic blood pressure in LR3 group after the short-term treatment and before acupuncture. (2) Compared with sham acupoint, acupuncture at LR3 instantaneous effects in the functional connectivity with seed points was more concentrated in the frontal lobe. (3) Compared with instantaneous effects, acupuncture LR3 short-term effects in the functional connectivity with seed points had more regions in frontal lobe, cerebellum, and insula. These brain areas constituted a neural network structure with specific functions that could explain the mechanism of therapy in hypertension patients by LR3 acupoint.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.