ArticleThe Journal of international medical research2016
Evaluation of a liquid culture system in the detection of mycobacteria at an antituberculosis institution in China; A retrospective study.
Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Article
- Article
- Effectiveness and trend forecasting of tuberculosis diagnosis after the introduction of GeneXpert in a city in south-eastern Brazil.PloS one · 2021Article
- Advances in diagnosis of Tuberculosis: an update into molecular diagnosis of Mycobacterium tuberculosis.Molecular biology reports · 2020Review
- Evaluation of a manual identification system for detection of Mycobacterium tuberculosis in a primary tuberculosis laboratory in China.The Journal of international medical research · 2019Article
- Evaluation of GeneXpert MTB/RIF for detecting Mycobacterium tuberculosis in a hospital in China.The Journal of international medical research · 2017Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective A retrospective study comparing the diagnostic performance of the BACTEC™ MGIT™ 960 system (M960 system; BD Worldwide, Franklin Lakes, NJ, USA) with Löwenstein-Jensen (L-J) culture to detect mycobacteria in sputum specimens from patients with suspected pulmonary tuberculosis (TB). Methods Sputum samples were analysed for the presence of acid-fast bacilli (AFB). Samples were inoculated into the M960 system and L-J culture. Positive cultures were examined for the presence of AFB. Results The M960 method detected significantly more positive samples than L-J culture (818/1676 [48.8%] vs 692/1676 [41.3%]). Using L-J culture as reference, the sensitivity, specificity, positive predictive and negative predictive values of the M960 system were 91.0%, 76.1%, 77.0% and 92.2%, respectively. The time-to-detection of mycobacteria was 11.78 ± 5.16 days for M960 and 24.17 ± 8.73 days for L-J. Conclusions The M960 system had better diagnostic capability than L-J culture. Clinical value may be maximized by combining results from both methods.
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