ReviewWorld journal of gastroenterology2016
Inflammatory bowel disease in India - Past, present and future.
Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Cross-national comparison of inflammatory bowel disease burden in China, Japan, the United States, and India: An age-period-cohort analysis of GBD 2021.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- Phenotypic Differences and Clinical Outcomes of South Asian Children With IBD: A Singapore-Malaysia Study From the Asian PIBD Registry Network.Journal of gastroenterology and hepatology · 2025Article
- The Autonomic Nervous System in Acupuncture for Gastrointestinal Dysmotility: From Anatomical Insights to Clinical Medicine.International journal of medical sciences · 2025Review
- Annexin A1 and A2 in inflammatory bowel disease pathogenesis: exploring new avenues for diagnosis and treatment.Frontiers in immunology · 2025Review
- Caregiver burden of IBD patients in Asian Emerging Nations is significant and necessitates attention and resource allocation.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Article
- Mangiferin, A Naturally Occurring Glucosylxanthone, Induces Apoptosis in Caco-2 CellsACS pharmacology & translational science · 2024Article
- Perianal fistulizing Crohn's disease: Current perspectives on diagnosis, monitoring and management with a focus on emerging therapies.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Inflammatory bowel disease: a narrative review of disease evolution in South Asia and India over the last decade.Therapeutic advances in gastroenterology · 2024Review
- Time trends in the burden of autoimmune diseases across the BRICS: an age-period-cohort analysis for the GBD 2019.RMD open · 2023Article
- Biofilm's Impact on Inflammatory Bowel Diseases.Cureus · 2023Review
- Sinigrin Attenuates the Dextran Sulfate Sodium-induced Colitis in Mice by Modulating the MAPK Pathway.Inflammation · 2023Article
- Inflammatory bowel disease associated knowledge in South Indian populations: rational Study.African health sciences · 2023Article
- Late onset crohns ileitis-A diagnostic dilemma.Journal of family medicine and primary care · 2022Article
- Newly Diagnosed Crohn's Disease Patients in India and Israel Display Distinct Presentations and Serological Markers: Insights from Prospective Cohorts.Journal of clinical medicine · 2022Article
- Epidemiological characteristics of Asian children with inflammatory bowel disease at diagnosis: Insights from an Asian-Pacific multi-centre registry network.World journal of gastroenterology · 2022Article
- Inflammatory bowel diseases in Tamil Nadu: A survey of demographics, clinical profile, and practices.JGH open : an open access journal of gastroenterology and hepatology · 2021Article
- Pediatric inflammatory bowel disease: Is it really uncommon in Asian children?JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Long-term outcomes in perianal fistulizing Crohn's disease in a resource-limited setting: A cohort analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020Article
- Prevalence of low bone mineral density in inflammatory bowel disease and factors associated with it.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020Article
- Secondary causes of inflammatory bowel diseases.World journal of gastroenterology · 2020Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is rising incidence and prevalence of inflammatory bowel disease (IBD) in India topping the Southeast Asian (SEA) countries. The common genes implicated in disease pathogenesis in the West are not causal in Indian patients and the role of "hygiene hypothesis" is unclear. There appears to be a North-South divide with more ulcerative colitis (UC) in north and Crohn's disease (CD) in south India. IBD in second generation Indian migrants to the West takes the early onset and more severe form of the West whereas it retains the nature of its country of origin in migrants to SEA countries. The clinical presentation is much like other SEA countries (similar age and sex profile, low positive family history and effect of smoking, roughly similar disease location, use of aminosalicylates for CD, low use of biologics and similar surgical rates) with some differences (higher incidence of inflammatory CD, lower perianal disease, higher use of aminosalicylates and azathioprine and lower current use of corticosteroids). UC presents more with extensive disease not paralleled in severity clinically or histologically, follows benign course with easy medical control and low incidence of fulminant disease, cancer, complications, and surgery. UC related colorectal cancer develop in an unpredictable manner with respect to disease duration and site questioning the validity of strict screening protocol. About a third of CD patients get antituberculosis drugs and a significant number presents with small intestinal bleed which is predominantly afflicted by aggressive inflammation. Biomarkers have inadequate diagnostic sensitivity and specificity for both. Pediatric IBD tends to be more severe than adult. Population based studies are needed to address the lacunae in epidemiology and definition of etiological factors. Newer biomarkers and advanced diagnostic techniques (in the field of gastrointestinal endoscopy, molecular pathology and genetics) needs to be developed for proper disease definition and treatment.
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