Evidence map›Paper›PMID 27688295›Full record

ArticleJournal of the National Cancer Institute2017

Biospecimen Sharing Among Hispanic Women in a Safety-Net Clinic: Implications for the Precision Medicine Initiative.

Jesse N Nodora, Ian K Komenaka, Marcia E Bouton, Lucila Ohno-Machado, Richard Schwab, Hyeon-Eui Kim, Claudiu Farcas, Giovanna Perez, Maria Elena Martinez

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jesse N NodoraMoores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Ian K KomenakaDepartment of Surgery, Maricopa Medical Center, Phoenix, AZ, USA.
Marcia E BoutonDepartment of Surgery, Maricopa Medical Center, Phoenix, AZ, USA.
Lucila Ohno-MachadoDepartment of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Richard SchwabMoores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Hyeon-Eui KimDepartment of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Claudiu FarcasDepartment of Biomedical Informatics, University of California, San Diego, La Jolla, CA, USA.
Giovanna PerezMoores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Maria Elena MartinezMoores Cancer Center, University of California, San Diego, La Jolla, CA, USA.

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Research Education CoreU54CA132379 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARREDONDO, ELVA M, CROWE, SHEILA E. · 2008 to 2021
$16.1M
NCI NIH HHS P30 CA023100NCI NIH HHS U54 CA132379NCI NIH HHS U54 CA132384
6 · The paper itself

Abstract

Biospecimen donation is key to the Precision Medicine Initiative, which pioneers a model for accelerating biomedical research through individualized care. Personalized medicine should be made available to medically underserved populations, including the large and growing US Hispanic population. We present results of a study of 140 Hispanic women who underwent a breast biopsy at a safety-net hospital and were randomly assigned to receive information and request for consent for biospecimen and data sharing by the patient's physician or a research assistant. Consent rates were high (97.1% and 92.9% in the physician and research assistant arms, respectively) and not different between groups (relative risk [RR] = 1.05, 95% confidence interval [CI] = 0.96 to 1.10). Consistent with a small but growing literature, we show that perceptions of Hispanics' unwillingness to participate in biospecimen sharing for research are not supported by data. Safety-net clinics and hospitals offer untapped possibilities for enhancing participation of underserved populations in the exciting Precision Medicine Initiative.

Indexed as

Biological Specimen BanksHispanic or LatinoInformation DisseminationInformed ConsentAdultBiopsyBreastCooperative BehaviorFemaleHumansMiddle AgedPrecision MedicineRandom AllocationSafety-net ProvidersVulnerable Populations

Identifiers

PMID27688295
PMCPMC5040829

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.