Evidence map›Paper›PMID 27688043›Full record

ArticleBMC health services research2016

Evaluation of medicine retail outlets for sale of typhoid fever vaccine among adults in two urban and rural settings in western Kenya: a proof-of-concept study.

Julius Ho, Gladys Odhiambo, Lucy W Meng'anyi, Rosemary M Musuva, Joseph M Mule, Zakayo S Alaly, Maurice R Odiere, Pauline N Mwinzi, Lisa Ganley-Leal

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Julius HoAlpert Medical School, Brown University, Providence, RI, USA.
Gladys OdhiamboImplementation Research Solutions (IRSK), Kakamega, Kenya.
Lucy W Meng'anyiKenyatta National Hospital, Nairobi, Kenya.
Rosemary M MusuvaImplementation Research Solutions (IRSK), Kakamega, Kenya.
Joseph M MuleImplementation Research Solutions (IRSK), Kakamega, Kenya.
Zakayo S AlalyImplementation Research Solutions (IRSK), Kakamega, Kenya.
Maurice R OdiereNeglected Tropical Diseases Branch, Centre for Global Health Research, Kenya Medical Research Institute, P. O. Box 1578-40100, Kisumu, Kenya. MOdiere@kemricdc.org.
Pauline N MwinziNeglected Tropical Diseases Branch, Centre for Global Health Research, Kenya Medical Research Institute, P. O. Box 1578-40100, Kisumu, Kenya.
Lisa Ganley-LealEpsilon Therapeutics, Inc., Newtown, USA.
Kenya Medical Research Institute · KEBrown University · USEpsilon Therapeutics (United States) · USKenyatta National Hospital · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrivate sector medicine outlets are an important provider of health services across the developing world, and are an untapped means of distributing and selling vaccines outside of childhood immunization programs. The present study assessed the viability of medicine outlets (chemists and pharmacies) as potential channels for sale of vaccines.

methodsTo evaluate the viability of the medicine outlet model, we partnered with nine outlets across urban and rural communities in western Kenya to sell a nurse-administered typhoid vaccine. Purchasers were surveyed to reveal market demographic characteristics, reasons for vaccine purchase, and sources of information about the program. Key informant interviews and focus group discussions defined acceptability, demand, and additional suggestions for improving this mechanism of selling and distributing vaccines.

resultsThere was a higher than expected demand for the vaccine that resulted in stock-outs. Previous instance of typhoid, desire to prevent disease, affordable price and convenience were cited by most participants as main reasons for purchase of vaccine at the local outlet. The most common source of information on the vaccine sale was word-of-mouth and referral from friends. Longer vaccine sale duration, adequate stocking of vaccines and extended hours of administration in the evening to allow working individuals to buy vaccines were cited by participants as ways for improved participation in the future.

conclusionsThis study demonstrated a high demand for vaccines at community medicine outlets. Important insights on how to improve and sustain such a program included extension of distribution time, education of outlet keepers, and minimizing vaccine stockouts. With improved social marketing, infrastructure mapping, education and pricing schemes, medicine outlets could become a sustainable avenue for selling adult vaccines in emerging markets for both routine and pandemic vaccines.

Identifiers

PMID27688043
PMCPMC5043612
OpenAlexW2527545649

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.