Evidence map›Paper›PMID 27688031›Full record

ArticleSurgery today2017

Safety and efficacy of an "enhanced recovery after surgery" protocol for patients undergoing colon cancer surgery: a multi-institutional controlled study.

Hirofumi Ota, Masakazu Ikenaga, Junichi Hasegawa, Kohei Murata, Yasuhiro Miyake, Tsunekazu Mizushima, Taishi Hata, Ichiro Takemasa, Hirofumi Yamamoto, Mitsugu Sekimoto and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgery today, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. IMPLEMENTATION OF ENHANCED RECOVERY AFTER COLORECTAL SURGERY (ERAS) PROTOCOL: INITIAL RESULTS OF THE FIRST BRAZILIAN EXPERIENCE.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hirofumi OtaDepartment of Digestive Surgery, Ikeda City Hospital, 3-1-18 Jyonan, Ikeda, Osaka, 563-8510, Japan. hirootajp@yahoo.co.jp.
Masakazu IkenagaDepartment of Surgery, Higashiosaka City General Hospital, Higashiosaka, Japan.
Junichi HasegawaDepartment of Surgery, Osaka Rosai Hospital, Sakai, Japan.
Kohei MurataDepartment of Surgery, Suita Municipal Hospital, Suita, Japan.
Yasuhiro MiyakeDepartment of Surgery, Nishinomiya Municipal Hospital, Nishinomiya, Japan.
Tsunekazu MizushimaDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Taishi HataDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Ichiro TakemasaDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Hirofumi YamamotoDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Mitsugu SekimotoDepartment of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Riichiro NezuDepartment of Surgery, Nishinomiya Municipal Hospital, Nishinomiya, Japan.
Yuichiro DokiDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Masaki MoriDepartment of Digestive Surgery, Osaka University Graduate School of Medicine, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this multi-institutional study was to prospectively evaluate the safety and efficacy of an enhanced recovery after surgery (ERAS) protocol for colonic surgery.

methodsThe subjects of this study were 320 patients with an American Society of Anesthesiologists (ASA) grade I or II physical status. Patients underwent elective open or laparoscopic colonic resection or high anterior resection between April 2011 and January 2014 at one of six institutions. Three hospitals implemented an ERAS protocol (n = 159), and three administered conventional care (n = 161). The primary outcome measure was the surgical complication rate.

resultsMost operations, irrespective of group, were performed laparoscopically. The incidence of a surgical complication was 17.0 % in the ERAS group vs. 16.1 % in the conventional group (P = 0.842), in which several non-surgical complications also arose. Oral food intake was implemented earlier for the ERAS group vs. the conventional group, after a median (range) of 1 (1-31) vs. 3 (1-9) days for the ERAS vs. conventional care groups, respectively (P < 0.001). The median length of postoperative hospital stay was reduced by 5.5 days for the ERAS group, being 8.5 (5-41) vs. 14 (7-56) days for the ERAS vs. conventional care groups, respectively (P < 0.001).

conclusionThis multi-institutional controlled study clearly demonstrated that an ERAS protocol was efficient, without increasing the complication risk.

Indexed as

Clinical ProtocolsAdultAgedAged, 80 and overColectomyColonic NeoplasmsElective Surgical ProceduresFemaleHumansIncidenceLaparoscopyLength of StayMaleMiddle AgedPerioperative CarePostoperative ComplicationsColon surgeryEnhanced recovery after surgeryMulti-institutional trial

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.