ArticleScientific reports2016
The domesticated brain: genetics of brain mass and brain structure in an avian species.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 65 citations in OpenAlex.
- Comprehensive transcriptomics comparison reveals switch of gene networks in the brain during silkworm domestication.Insect science · 2026Article
- Selection for Tameness in Red Junglefowl Recapitulates Genetic Loci Associated With Domestication-Related Brain Composition.Molecular ecology · 2025Article
- Larger Fish Have Larger Brains With More Neurons Across but Not Within Cohorts Raised in Different Growth Conditions.The Journal of comparative neurology · 2025Article
- Welfare of American mink, red and Arctic foxes, raccoon dog and chinchilla kept for fur production.EFSA journal. European Food Safety Authority · 2025Article
- Domestication effects on crowing in chickens: variation between wild and captive red junglefowl and domestic white Leghorn and the genetic architecture of crowing vocalizations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Selection for tameness alters play-like behaviour in red junglefowl in line with effects of domestication.Biology letters · 2025Article
- Brain shapes of large-bodied, flightless ratites (Aves: Palaeognathae) emerge through distinct developmental allometries.Royal Society open science · 2024Article
- Association of tameness and sociability but no sign of domestication syndrome in mice selectively bred for active tameness.Genes, brain, and behavior · 2024Article
- Selection for Reduced Fear of Humans Changes Brain and Cerebellum Size in Red Junglefowl in Line with Effects of Chicken Domestication.Brain sciences · 2023Article
- Neuronal and non-neuronal scaling across brain regions within an intercross of domestic and wild chickens.Frontiers in neuroanatomy · 2022Article
- Proportional Cerebellum Size Predicts Fear Habituation in Chickens.Frontiers in physiology · 2022Article
- The cerebellar anatomy of red junglefowl and white leghorn chickens: insights into the effects of domestication on the cerebellum.Royal Society open science · 2021Article
- Domestication-induced reduction in eye size revealed in multiple common garden experiments: The case of Atlantic salmon (Evolutionary applications · 2021Article
- Article
- An agent-based model clarifies the importance of functional and developmental integration in shaping brain evolution.BMC biology · 2021Article
- Tameness correlates with domestication related traits in a Red Junglefowl intercross.Genes, brain, and behavior · 2021Article
- Cerebellum size is related to fear memory and domestication of chickens.Biology letters · 2021Article
- The methylation landscape and its role in domestication and gene regulation in the chicken.Nature ecology & evolution · 2020Article
- Intra-Individual Behavioural Variability: A Trait under Genetic Control.International journal of molecular sciences · 2020Article
- Selection for reduced fear in red junglefowl changes brain composition and affects fear memory.Royal Society open science · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As brain size usually increases with body size it has been assumed that the two are tightly constrained and evolutionary studies have therefore often been based on relative brain size (i.e. brain size proportional to body size) rather than absolute brain size. The process of domestication offers an excellent opportunity to disentangle the linkage between body and brain mass due to the extreme selection for increased body mass that has occurred. By breeding an intercross between domestic chicken and their wild progenitor, we address this relationship by simultaneously mapping the genes that control inter-population variation in brain mass and body mass. Loci controlling variation in brain mass and body mass have separate genetic architectures and are therefore not directly constrained. Genetic mapping of brain regions indicates that domestication has led to a larger body mass and to a lesser extent a larger absolute brain mass in chickens, mainly due to enlargement of the cerebellum. Domestication has traditionally been linked to brain mass regression, based on measurements of relative brain mass, which confounds the large body mass augmentation due to domestication. Our results refute this concept in the chicken.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.