Evidence map›Paper›PMID 27687755›Full record

ReviewVirulence2016

Aspergillosis and stem cell transplantation: An overview of experimental pathogenesis studies.

Nadia Al-Bader, Donald C Sheppard

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trans-Kingdom dsRNA Sensing:bioRxiv : the preprint server for biology · 2026
    Article
  2. Pathogenesis and Triazole Resistance inInfection and drug resistance · 2026
    Review
  3. Review
  4. Managing Invasive Fungal Infections During Allogeneic Hematopoietic Transplantation: A 2025 Update.Mediterranean journal of hematology and infectious diseases · 2025
    Review
  5. Article
  6. Epidemiology of Clinically SignificantInfection and drug resistance · 2023
    Article
  7. Article
  8. Protective role of host complement system inFrontiers in immunology · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. How Long Do We Need to Treat an Invasive Mold Disease in Hematology Patients? Factors Influencing Duration of Therapy and Future Questions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  13. The Journal of biological chemistry · 2018
    Article
  14. Linear Epitopes ofFrontiers in immunology · 2017
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nadia Al-Badera Departments of Medicine, Microbiology and Immunology , McGill University , Montréal , Québec , Canada.
Donald C Shepparda Departments of Medicine, Microbiology and Immunology , McGill University , Montréal , Québec , Canada.
McGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive aspergillosis is a life-threatening infection caused by the opportunistic filamentous fungus Aspergillus fumigatus. Patients undergoing haematopoietic stem cell transplant (HSCT) for the treatment of hematological malignancy are at particularly high risk of developing this fatal infection. The susceptibility of HSCT patients to infection with A. fumigatus is a consequence of a complex interplay of both fungal and host factors. Here we review our understanding of the host-pathogen interactions underlying the susceptibility of the immunocompromised host to infection with A. fumigatus with a focus on the experimental validation of fungal and host factors relevant to HSCT patients. These include fungal factors such as secondary metabolites, cell wall constituents, and metabolic adaptations that facilitate immune evasion and survival within the host microenvironment, as well as the innate and adaptive immune responses involved in host defense against A. fumigatus.

Indexed as

Host-Pathogen InteractionsAspergillus fumigatusHematologic NeoplasmsHumansImmune EvasionImmunity, InnateImmunocompromised HostInvasive Pulmonary AspergillosisStem Cell TransplantationVirulenceaspergillosisaspergillusimmunitypathogenesisstem cell transplantvirulence

Identifiers

PMID27687755
PMCPMC5160406
OpenAlexW2525605172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.