ArticleMolecular biology and evolution2016
A Thousand Fly Genomes: An Expanded Drosophila Genome Nexus.
Article in Molecular biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.
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Who cites it
108 citing papers in PubMed.
- Article
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- Strain variation identifies a neural substrate for behavioral evolution in Drosophila.Current biology : CB · 2026Article
- Evolution of Plasticity in Response to Ethanol Between Recently Separated Populations ofEcology and evolution · 2026Article
- Retention of a singlebioRxiv : the preprint server for biology · 2025Article
- Gene age shapes functional and evolutionary properties of theProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Functional characterization of Paillotin: an immune peptide regulated by the Immune deficiency (Imd) pathway with pathogen-specific roles inProceedings. Biological sciences · 2025Article
- Strain variation identifies a neural substrate for behavioral evolution inbioRxiv : the preprint server for biology · 2025Article
- Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations ofEvolution letters · 2025Article
- Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource.Molecular biology and evolution · 2025Article
- Spatiotemporal Tracking of Three Novel Transposable Element Invasions in Drosophila melanogaster over the Last 30 Years.Molecular biology and evolution · 2025Article
- Parameter Scaling in Population Genetics Simulations may Introduce Unintended Background Selection: Considerations for Scaled Simulation Design.Genome biology and evolution · 2025Article
- Courtship song differs between African and European populations of Drosophila melanogaster and involves a strong effect locus.G3 (Bethesda, Md.) · 2025Article
- Establishing genome sequencing and assembly for non-model and emerging model organisms: a brief guide.Frontiers in zoology · 2025Review
- The potential of inversions to accumulate balanced sexual antagonism is supported by simulations andeLife · 2025Article
- Latitudinal Clines in Climate and Sleep Patterns Shape Disease Outcomes inEcology and evolution · 2025Article
- How to Validate a Bayesian Evolutionary Model.Systematic biology · 2025Article
- The Influence of Chromosomal Inversions on Genetic Variation and Clinal Patterns in Genomic Data of Drosophila melanogaster.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Cis-regulatory Variation in Relation to Sex and Sexual Dimorphism in Drosophila melanogaster.Genome biology and evolution · 2024Article
48 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
The Drosophila Genome Nexus is a population genomic resource that provides D. melanogaster genomes from multiple sources. To facilitate comparisons across data sets, genomes are aligned using a common reference alignment pipeline which involves two rounds of mapping. Regions of residual heterozygosity, identity-by-descent, and recent population admixture are annotated to enable data filtering based on the user's needs. Here, we present a significant expansion of the Drosophila Genome Nexus, which brings the current data object to a total of 1,121 wild-derived genomes. New additions include 305 previously unpublished genomes from inbred lines representing six population samples in Egypt, Ethiopia, France, and South Africa, along with another 193 genomes added from recently-published data sets. We also provide an aligned D. simulans genome to facilitate divergence comparisons. This improved resource will broaden the range of population genomic questions that can addressed from multi-population allele frequencies and haplotypes in this model species. The larger set of genomes will also enhance the discovery of functionally relevant natural variation that exists within and between populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.