Evidence map›Paper›PMID 27687020›Full record

ArticleLupus2017

Long-term systemic lupus erythematosus disease control after allogeneic bone marrow transplantation.

D E Gladstone, M Petri, J Bolaños-Meade, A E Dezern, R J Jones, D Fine, R A Brodsky

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Lupus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Stem cell-based therapy for systemic lupus erythematous.Journal of translational autoimmunity · 2024
    Review
  2. Article
  3. Haemopoietic stem cell transplantation in Systemic lupus erythematosus: a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

D E GladstoneJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
M PetriJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
J Bolaños-MeadeJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
A E DezernJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
R J JonesJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
D FineJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
R A BrodskyJohns Hopkins Hospital and Health System, Baltimore, MD, USA.
Johns Hopkins Hospital · US

Funding

TUMOR VACCINESP01CA015396 · NCI · JOHNS HOPKINS UNIVERSITY · PI HESS, ALLAN D · 1985 to 2016
$38.1M
NCI NIH HHS P01 CA015396
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE), a disorder of the immune system, is potentially curable by allogeneic bone marrow transplantation (alloBMT). Until recently, alloBMT was limited by donor availability and toxicity. Reduced intensity conditioning (RIC) combined with post-transplantation cyclophosphamide (PTCy) has improved the availability and safety of alloBMT permitting its exploration in severe-refractory autoimmune illnesses. We report the six-year follow-up of a young female whose refractory SLE-associated nephrosis resolved after RIC alloBMT with PTCy.

Indexed as

AdultBone Marrow TransplantationCyclophosphamideFemaleFollow-Up StudiesHumansImmunosuppressive AgentsLupus Erythematosus, SystemicTransplantation ConditioningTransplantation, HomologousTreatment OutcomeCyclophosphamideImmunosuppressive AgentsalloBMTSystemic lupus erythematosus

Identifiers

PMID27687020
PMCPMC5374037
OpenAlexW2524008134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.