Evidence map›Paper›PMID 27686814›Full record

ArticleCytotechnology2016

In vitro cytotoxic and genotoxic evaluation of peptides used in nuclear medicine (DOTATATE and Ubiquicidin

Ivette Zegarra Ocampo, Priscila de Queiroz Souza Passos, Luma Ramirez de Carvalho, Camila Ayala Lira da Cruz, Natália Mencacci Esteves-Pedro, Fabiana Medeiros da Silva, Olga Zazuco Higa, Luiz Alberto Pereira Dias, Kayo Okazaki, Daniel Perez Vieira

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cytotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ivette Zegarra OcampoLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil.
Priscila de Queiroz Souza PassosBiosynthesis Laboratory, São Paulo, SP, Brazil.
Luma Ramirez de CarvalhoLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil.
Camila Ayala Lira da CruzLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil.
Natália Mencacci Esteves-PedroBiosynthesis Laboratory, São Paulo, SP, Brazil.
Fabiana Medeiros da SilvaBiosynthesis Laboratory, São Paulo, SP, Brazil.
Olga Zazuco HigaLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil.
Luiz Alberto Pereira DiasCenter of Radiopharmacy, Quality Control Management, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, São Paulo, SP, Brazil.
Kayo OkazakiLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil.
Daniel Perez VieiraLaboratory of Radiobiology, Center of Biotechnology, Institute of Nuclear and Energetic Research IPEN/CNEN-SP, Av. LineuPrestes, 2242, São Paulo, SP, 05508-000, Brazil. dpvieira@ipen.br.
National Nuclear Energy Commission · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micronucleus (MN) assay constitutes a valuable surrogate to the chromosome aberration technique for in vitro testing of the genotoxicity of substances. As test substances, two peptidic compounds (DOTATATE and Ubiquicidin

Indexed as

CHO-K1 cellCytotoxicityDOTATATE, Ubiquicidin29-41GenotoxicityModified micronucleus assay

Identifiers

PMID27686814
PMCPMC5101300
OpenAlexW2527463645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.