Evidence map›Paper›PMID 27686718›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2017

Microbiome and food allergy.

Ana B Blázquez, M Cecilia Berin

Open access · greenAbstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Impact of oral immunotherapy on diversity of gut microbiota in food-allergic children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Gut microbiome is associated with asthma and race in children with food allergy.The Journal of allergy and clinical immunology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. The Environmental Microbiome, Allergic Disease, and Asthma.The journal of allergy and clinical immunology. In practice · 2022
    Article
  15. Detection ofFrontiers in veterinary science · 2022
    Article
  16. Review
  17. Article
  18. Association between intestinal neoplasms and celiac disease: A review.World journal of gastrointestinal oncology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ana B BlázquezJaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
M Cecilia BerinJaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: cecilia.berin@mssm.edu.
Icahn School of Medicine at Mount Sinai · US

Funding

Role of T cells in gastrointestinal manifestations of food allergyR01AI093577 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BERIN, CECILIA · 2012 to 2016
$2.1M
Communication between skin and gastrointestinal tract in food allergyR21AI124062 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BERIN, CECILIA · 2016 to 2017
$466k
NIAID NIH HHS R01 AI093577NIAID NIH HHS R21 AI124062
6 · The paper itself

Abstract

Food allergy is a common disease affecting approximately 8% of children and 5% of adults. The prevalence has increased over the last two decades, suggesting an important environmental contribution to susceptibility. Studies have identified mode of birth, pet exposure, and having older siblings as being significant risk modifying factors in the development of food allergy. With the discovery that these factors significantly impact the composition of the intestinal microbiome, which is known to play a critical role in shaping the immune system, recent studies have begun to address the role of the intestinal microbiota in the development of food allergy. Studies in human cohorts support a dysbiosis in food allergy, and limited data suggest that this dysbiosis occurs early in life, preceding the onset of sensitization. Studies from animal models have clearly shown that the composition of the intestinal microbiota confers susceptibility to food allergy, and that there are organisms such as Clostridia species that are protective in the development of food allergy. Our understanding of microbial regulation of food allergy is in its nascency, but the state of the field supports an important contribution of intestinal microbes to susceptibility. Challenges going forward are to identify commensal-derived microorganisms that could be used therapeutically to prevent or perhaps treat food allergy.

Indexed as

MicrobiotaAnimalsColony Count, MicrobialDisease Models, AnimalFood HypersensitivityGastrointestinal MicrobiomeGastrointestinal TractHumans

Identifiers

PMID27686718
PMCPMC5164970
OpenAlexW2519342063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.