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ArticleEcho research and practice2016

A meta-analysis for echocardiographic assessment of right ventricular structure and function in ARVC.

M Qasem, V Utomi, K George, J Somauroo, A Zaidi, L Forsythe, S Bhattacharrya, G Lloyd, B Rana, L Ring and 9 more

Open access · goldAbstract read
In one paragraph

Article in Echo research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. State-of-the-Art in Echocardiographic Strain Imaging of Arrhythmogenic Cardiomyopathy.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

M QasemM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
V UtomiM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
K GeorgeM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
J SomaurooM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
A ZaidiM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
L ForsytheM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
S BhattacharryaM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
G LloydM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
B RanaM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
L RingM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
S RobinsonM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
R SeniorM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
N SheikhM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
M SitaliM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
J SandovalM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
R SteedsM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
M StoutM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
J WillisM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
D OxboroughM Qasem, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKV Utomi, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKK George, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKJ Somauroo, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKA Zaidi, Barts Heart Centre, St Bartholomew's Hospital, London, UKL Forsythe, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UKS Bhattacharrya, Barts Heart Centre, St Bartholomew's Hospital, London, UKG Lloyd, Barts Heart Centre, St Bartholomew's Hospital, London, UKB Rana, Papworth Hospital NHS Trust, Cambridge, UKL Ring, West Suffolk NHS Trust, Bury St Edmonds, UKS Robinson, Papworth Hospital NHS Trust, Cambridge, UKR Senior, National Heart and Lung Institute, Imperial College, London, UKN Sheikh, St Georges University Hospital, London, UKM Sitali, Guys and St Thomas's NHS Trust, London, UKJ Sandoval, Leeds Teaching Hospitals NHS Trust, Leeds, UKR Steeds, University Hospitals Birmingham NHS Trust and Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UKM Stout, Cardiology Department, University Hospital of South Manchester, Manchester, UKJ Willis, Royal United Hospital, Bath, UKD Oxborough, Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Middlesbrough, UK.
Liverpool John Moores University · GBSt Bartholomew's Hospital · GBImperial College London · GBLeeds Teaching Hospitals NHS Trust · GBRoyal United Hospital · GBSt George's Hospital · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionArrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited pathology that can increase the risk of sudden death. Current Task Force Criteria for echocardiographic diagnosis do not include new, regional assessment tools which may be relevant in a phenotypically diverse disease. We adopted a systematic review and meta-analysis approach to highlight echocardiographic indices that differentiated ARVC patients and healthy controls.

methodsData was extracted and analysed from prospective trials that employed a case-control design meeting strict inclusion and exclusion as well as a-priori quality criteria. Structural indices included proximal RV outflow tract(RVOT1) and RV diastolic area(RVDarea). Functional indices included RV fractional area change (RVFAC), Tricuspid Annular Systolic Excursion(TAPSE), peak systolic and early diastolic myocardial velocities (S' and E' respectively) and myocardial strain.

resultsPatients with ARVC had larger RVOT1 (mean  SD; 34 vs. 28 mm P<0.001) and RVDarea (23 vs. 18 cm2 P<0.001) compared to healthy controls. ARVC patients also had lower RVFAC (38 vs. 46 % P<0.001), TAPSE(17 vs. 23 mm P<0.001), S' (9 vs. 12 cm.s-1 P<0.001), E' (9 vs. 13 cm.s-1 P<0.001) and myocardial strain (-17 vs. -30% P<0.001).

conclusionThe data from this meta-analysis support current Task Force criteria for the diagnosis of ARVC. In addition, other RV measures that reflect the complex geometry and function in ARVC clearly differentiated between ARVC and healthy controls and may provide additional diagnostic and management value. We recommend that future working groups consider this data when proposing new / revised criteria for the echocardiographic diagnosis of ARVC.

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PMID27686556
PMCPMC5076568
OpenAlexW2535457224

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