Evidence map›Paper›PMID 27686370›Full record

Trial reportMaternal & child nutrition2017

Nutritional status and complementary feeding among HIV-exposed infants: a prospective cohort study.

Pili Kamenju, Enju Liu, Ellen Hertzmark, Donna Spiegelman, Rodrick Kisenge, Roland Kupka, Said Aboud, Karim P Manji, Christopher Duggan, Wafaie W Fawzi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Maternal & child nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Pili KamenjuHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Enju LiuHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Ellen HertzmarkHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Donna SpiegelmanHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Rodrick KisengeMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Roland KupkaHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Said AboudMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Karim P ManjiMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Christopher DugganHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Wafaie W FawziHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Harvard University · USMuhimbili University of Health and Allied Sciences · TZ

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JERROLD R. TURNER · 1986 to 2026
$32.4M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Trial of Vitamins among Children of HIV-infected MothersR01HD043688 · NICHD · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI FAWZI, WAFAIE W · 2003 to 2007
$2.7M
Tanzania Infectious Disease Research Training ProgramD43TW007886 · FIC · HARVARD SCHOOL OF PUBLIC HEALTH · PI FAWZI, WAFAIE W · 2007 to 2018
$1.9M
Patient-oriented Research in Pediatric Diarrheal DiseasesK24DK104676 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI DUGGAN, CHRISTOPHER P · 2015 to 2019
$903k
FIC NIH HHS D43 TW007886NICHD NIH HHS R01 HD043688NIDDK NIH HHS K24 DK104676NIDDK NIH HHS P30 DK034854NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Complementary feeding is crucial for improving child survival and promoting growth and development, particularly among HIV-exposed children who have higher risk of morbidity and mortality than their un-exposed peers. This prospective study employed an infant and child feeding index (ICFI) to measure complementary feeding and determine its association with nutritional status among 2092 HIV-exposed infants followed from 6 to 24 months of age in Dar es Salaam, Tanzania. The ICFI measured both quality and quantity of complementary feeding, including current breastfeeding status, food consistency, dietary diversity scores (DDS), food group frequency score, and meal frequency. The ICFI score ranged from 0 to 9; the median score was 6 (Inter-Quartile Range, IQR= 4-7). After adjusting for potential confounders, high ICFI scores were associated with reduced risk of stunting (high vs. low tertile hazard ratio, HR: 0.72; 95% confidence interval, CI: 0.57, 0.91; P< 0.01) and underweight (high vs. low tertile HR: 0.79; 95% CI: 0.61, 1.02; P= 0.07). Low DDS were associated with higher risk of stunting (low vs. high tertile HR: 1.59; 95% CI: 1.23, 2.07; P< 0.01) and underweight (low vs. high tertile HR: 1.48; 95% CI: 1.12, 1.96; P= 0.01). In this setting, high DDS and ICFI scores were protective of stunting and underweight. We recommend for nutrition programs in low-income countries to emphasize educating HIV-exposed children's caregivers on the importance of dietary diversity and optimal complementary feeding to improve nutritional status in this important subpopulation.

Indexed as

Infant Nutritional Physiological PhenomenaNutritional StatusAdultChild, PreschoolDietDouble-Blind MethodFollow-Up StudiesGrowth DisordersHIV InfectionsHumansInfantInfant FoodNutrition AssessmentProspective StudiesSocioeconomic FactorsTanzaniachild growthcomplementary feedingHIV and infant feedinginfant and child nutritionlow income countriesundernutrition

Identifiers

PMID27686370
PMCPMC5654526
OpenAlexW2528178726

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.