Evidence map›Paper›PMID 27686352›Full record

ArticleIntensive care medicine2017

The effects of performance status one week before hospital admission on the outcomes of critically ill patients.

Fernando G Zampieri, Fernando A Bozza, Giulliana M Moralez, Débora D S Mazza, Alexandre V Scotti, Marcelo S Santino, Rubens A B Ribeiro, Edison M Rodrigues Filho, Maurício M Cabral, Marcelo O Maia and 10 more

Abstract read
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In one paragraph

Article in Intensive care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Quantifying the burden of the post-ICU syndrome in South Africa: A scoping review of evidence from the public health sector.The Southern African journal of critical care : the official journal of the Critical Care Society · 2022
    Article
  19. Cardiogenic shock among cancer patients.Frontiers in cardiovascular medicine · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Fernando G ZampieriResearch Institute, Hospital do Coração (HCor), São Paulo, Brazil.
Fernando A BozzaDepartment of Critical Care, D'Or Institute for Research and Education, Rua Diniz Cordeiro, 30, Botafogo, Rio de Janeiro, 22281-100, Brazil.
Giulliana M MoralezDepartment of Critical Care, D'Or Institute for Research and Education, Rua Diniz Cordeiro, 30, Botafogo, Rio de Janeiro, 22281-100, Brazil.
Débora D S MazzaIntensive Care Unit, Hospital São Luiz-Unidade Jabaquara, São Paulo, Brazil.
Alexandre V ScottiIntensive Care Unit, Hospital Israelita Albert Sabin, Rio de Janeiro, Brazil.
Marcelo S SantinoIntensive Care Unit, Hospital Barra D'Or, Rio de Janeiro, Brazil.
Rubens A B RibeiroIntensive Care Unit, Hospital Anchieta, Taguatinga, Brazil.
Edison M Rodrigues FilhoComplexo Hospitalar Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
Maurício M CabralIntensive Care Unit, Hospital São Marcos, Recife, Brazil.
Marcelo O MaiaIntensive Care Unit, Hospital Santa Luzia, Brasília, Brazil.
Patrícia S D'AlessandroIntensive Care Unit, Clínica São Vicente, Rio de Janeiro, Brazil.
Sandro V OliveiraIntensive Care Unit, Hospital Bangu, Rio de Janeiro, Brazil.
Márcia A M MenezesIntensive Care Unit, Hospital Oeste D'Or, Rio de Janeiro, Brazil.
Eliana B CaserIntensive Care Unit, Hospital Unimed Vitória, Vitória, Brazil.
Roberto S LannesIntensive Care Unit, Hospital Municipal Souza Aguiar, Rio de Janeiro, Brazil.
Meton S Alencar NetoIntensive Care Unit, Hospital Regional do Cariri, Juazeiro do Norte, Brazil.
Maristela M MachadoIntensive Care Unit, Hospital Agenor Paiva, Salvador, Brazil.
Marcelo F SousaIntensive Care Unit, Santa Casa de Caridade de Diamantina, Diamantina, Brazil.
Jorge I F SalluhDepartment of Critical Care, D'Or Institute for Research and Education, Rua Diniz Cordeiro, 30, Botafogo, Rio de Janeiro, 22281-100, Brazil.
Marcio SoaresDepartment of Critical Care, D'Or Institute for Research and Education, Rua Diniz Cordeiro, 30, Botafogo, Rio de Janeiro, 22281-100, Brazil. marciosoaresms@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the impact of performance status (PS) impairment 1 week before hospital admission on the outcomes in patients admitted to intensive care units (ICU).

methodsRetrospective cohort study in 59,693 patients (medical admissions, 67 %) admitted to 78 ICUs during 2013. We classified PS impairment according to the Eastern Cooperative Oncology Group (ECOG) scale in absent/minor (PS = 0-1), moderate (PS = 2) or severe (PS = 3-4). We used univariate and multivariate logistic regression analyses to investigate the association between PS impairment and hospital mortality.

resultsPS impairment was moderate in 17.3 % and severe in 6.9 % of patients. The hospital mortality was 14.4 %. Overall, the worse the PS, the higher the ICU and hospital mortality and length of stay. In addition, patients with worse PS were less frequently discharged home. PS impairment was associated with worse outcomes in all SAPS 3, Charlson Comorbidity Index and age quartiles as well as according to the admission type. Adjusting for other relevant clinical characteristics, PS impairment was associated with higher hospital mortality (odds-ratio (OR) = 1.96 (95 % CI 1.63-2.35), for moderate and OR = 4.22 (3.32-5.35), for severe impairment). The effects of PS on the outcome were particularly relevant in the medium range of severity-of-illness. These results were consistent in the subgroup analyses. However, adding PS impairment to the SAPS 3 score improved only slightly its discriminative capability.

conclusionPS impairment was associated with worse outcomes independently of other markers of chronic health status, particularly for patients in the medium range of severity of illness.

Indexed as

Health StatusHealth Status IndicatorsAdultAgedAged, 80 and overCohort StudiesCritical IllnessFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexTreatment OutcomeCritical careMarkers of baseline health statusOutcomesPerformance status

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.