Evidence map›Paper›PMID 27686232›Full record

Observational studyObesity surgery2017

Predictive Value of C-Reactive Protein for Complications Post-Laparoscopic Roux-En-Y Gastric Bypass.

Murray R Williams, Samuel McMeekin, R Jonathan T Wilson, Glenn V Miller, Fiona E Langlands, Wingzou Wong, Mark Peter, Mathew S Giles

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Murray R WilliamsDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK. murray.williams@york.nhs.uk.
Samuel McMeekinDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
R Jonathan T WilsonDepartment of Anaesthetics, York Teaching Hospitals NHS Trust, York, UK.
Glenn V MillerDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
Fiona E LanglandsDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
Wingzou WongDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
Mark PeterDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
Mathew S GilesDepartment of Surgery, York Teaching Hospitals NHS Trust, York, UK.
York Teaching Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic roux-en-Y gastric bypass (LRYGB) has gained increasing popularity as the primary procedure of choice for the management of patients with morbid obesity. Despite the advances, a few patients will still develop complications and predicting these early complications in morbidly obese patients can prove to be difficult. Radiological investigations have limited diagnostic value and have associated side effects and cost. We propose that C-reactive protein (CRP) is a useful predictor for early postoperative complications. This study aims to determine the ability of CRP taken on postoperative day 1 (POD 1) and 2 to predict occurrence of complications within 30 days of surgery.

methodsThis retrospective observational study selected 183 consecutive patients from the York bariatric database between 01 December 2010 and 23 March 2015. EXCLUSIONS: Patients undergoing dual procedures, conversion to open, and if no postoperative CRP measurement was performed.

resultsIn total, 138 patients satisfied the inclusion criteria during the study period (median age 44 years [20-68], BMI 50.6 kg/m2 [38.3-62.5]). Fifteen (10.8 %) patients had minor complications (CD of 2) and 8 (5.6 %) had major complications (CD 3 or above). A CRP of greater than 127 mg/L on POD 2 was found to predict complications with 93 % sensitivity and 64 % specificity with diagnostic accuracy 0.82 (95 % confidence interval 0.731-0.908).

conclusionsIn our patients, CRP on POD 2 has been shown to be a good predictor of both minor and major complications and can therefore be used to guide clinicians in making decision as to which patients may need further investigation or who can be safely discharged.

Indexed as

AdultAgedBiomarkersC-Reactive ProteinFemaleGastric BypassHumansLaparoscopyLength of StayMaleMiddle AgedMorbidityObesity, MorbidPostoperative CarePostoperative ComplicationsPredictive Value of TestsBiomarkersC-Reactive ProteinBariatric surgeryC-reactive proteinCRPLaparoscopic roux-en Y gastric bypassPostoperative complicationsROC curve analysis

Identifiers

PMID27686232
OpenAlexW2524451191

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.