ArticleScientific reports2016
Development of dopant-free conductive bioelastomers.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Evaluating and improving biocompatibility of conductive polymers for cardiac tissue engineering.Journal of materials chemistry. B · 2026Review
- Synthesis and Polymerization of Thiophene-Bearing 2-Oxazolines and 2-Oxazines.Macromolecular rapid communications · 2025Article
- Bioresorbable Materials for Wound Management.Biomimetics (Basel, Switzerland) · 2025Review
- Highly Conducting and Ultra-Stretchable Wearable Ionic Liquid-Free Transducer for Wireless Monitoring of Physical Motions.Macromolecular rapid communications · 2024Article
- Ultra-stretchable and biodegradable elastomers for soft, transient electronics.Nature communications · 2023Article
- Synergetic Effect of Electrical and Topographical Cues in Aniline Trimer-Based Polyurethane Fibrous Scaffolds on Tissue Regeneration.Journal of functional biomaterials · 2023Article
- Toward Sustainable Wearable Electronic Textiles.ACS nano · 2022Review
- Rational design of biodegradable thermoplastic polyurethanes for tissue repair.Bioactive materials · 2022Review
- Biodegradable Elastomers and Gels for Elastic Electronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Review
- An Electroactive Oligo-EDOT Platform for Neural Tissue Engineering.Advanced functional materials · 2020Article
- Electroconductive Nanobiomaterials for Tissue Engineering and Regenerative Medicine.Bioelectricity · 2020Review
- Current advances in biodegradable synthetic polymer based cardiac patches.Journal of biomedical materials research. Part A · 2020Review
- Electrically Conductive Materials: Opportunities and Challenges in Tissue Engineering.Biomolecules · 2019Review
- Article
- Enhancing anti-thrombogenicity of biodegradable polyurethanes through drug molecule incorporation.Journal of materials chemistry. B · 2018Article
- Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction.Scientific reports · 2018Article
- Biodegradable Polymeric Materials in Degradable Electronic Devices.ACS central science · 2018Review
- Highly Elastic Biodegradable Single-Network Hydrogel for Cell Printing.ACS applied materials & interfaces · 2018Article
- Physicochemical properties and in vitro cytotoxicity of iron oxide-based nanoparticles modified with antiangiogenic and antitumor peptide A7R.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conductive biodegradable materials are of great interest for various biomedical applications, such as tissue repair and bioelectronics. They generally consist of multiple components, including biodegradable polymer/non-degradable conductive polymer/dopant, biodegradable conductive polymer/dopant or biodegradable polymer/non-degradable inorganic additives. The dopants or additives induce material instability that can be complex and possibly toxic. Material softness and elasticity are also highly expected for soft tissue repair and soft electronics. To address these concerns, we designed a unicomponent dopant-free conductive polyurethane elastomer (DCPU) by chemically linking biodegradable segments, conductive segments, and dopant molecules into one polymer chain. The DCPU films which had robust mechanical properties with high elasticity and conductivity can be degraded enzymatically and by hydrolysis. It exhibited great electrical stability in physiological environment with charge. Mouse 3T3 fibroblasts survived and proliferated on these films exhibiting good cytocompatibility. Polymer degradation products were non-toxic. DCPU could also be processed into a porous scaffold and in an in vivo subcutaneous implantation model, exhibited good tissue compatibility with extensive cell infiltration over 2 weeks. Such biodegradable DCPU with good flexibility and elasticity, processability, and electrical stability may find broad applications for tissue repair and soft/stretchable/wearable bioelectronics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.