Evidence map›Paper›PMID 27686111›Full record

ArticleCognitive neuropsychology

Using precise word timing information improves decoding accuracy in a multiband-accelerated multimodal reading experiment.

An T Vu, Jeffrey S Phillips, Kendrick Kay, Matthew E Phillips, Matthew R Johnson, Svetlana V Shinkareva, Shannon Tubridy, Rachel Millin, Murray Grossman, Todd Gureckis and 2 more

Abstract read
In one paragraph

Article in Cognitive neuropsychology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

An T Vua Center for Magnetic Resonance Research , University of Minnesota , Minneapolis , MN , USA.
Jeffrey S Phillipsb Department of Neurology , University of Pennsylvania , Philadelphia , PA , USA.
Kendrick Kayc Department of Psychology , Washington University in St. Louis , St. Louis , MO , USA.
Matthew E Phillipsd HRL Laboratories LLC , Malibu , CA , USA.
Matthew R Johnsone Department of Psychology , Yale University , New Haven , CT , USA.
Svetlana V Shinkarevaf Department of Psychology , University of South Carolina , Columbia , SC , USA.
Shannon Tubridyg Department of Psychology , New York University , New York , NY , USA.
Rachel Millind HRL Laboratories LLC , Malibu , CA , USA.
Murray Grossmanb Department of Neurology , University of Pennsylvania , Philadelphia , PA , USA.
Todd Gureckisg Department of Psychology , New York University , New York , NY , USA.
Rajan Bhattacharyyad HRL Laboratories LLC , Malibu , CA , USA.
Essa Yacouba Center for Magnetic Resonance Research , University of Minnesota , Minneapolis , MN , USA.

Funding

Transgenic Mouse Models of Tau PathologiesP01AG017586 · NIA · UNIVERSITY OF PENNSYLVANIA · PI LEE, VIRGINIA M · 2000 to 2021
$37.3M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Connectomic imaging in familial and sporadic frontotemporal degenerationU01AG052943 · NIA · UNIVERSITY OF PENNSYLVANIA · PI GORNO TEMPINI, MARIA LUISA, GROSSMAN, MURRAY · 2016 to 2019
$5.9M
Age, Hearing Loss, and Sentence Comprehension: Neural CorrelatesR01AG038490 · NIA · UNIVERSITY OF PENNSYLVANIA · PI GROSSMAN, MURRAY · 2012 to 2016
$2.1M
NIA NIH HHS P01 AG017586NIA NIH HHS R01 AG038490NIA NIH HHS U01 AG052943NIBIB NIH HHS P41 EB015894
6 · The paper itself

Abstract

The blood-oxygen-level-dependent (BOLD) signal measured in functional magnetic resonance imaging (fMRI) experiments is generally regarded as sluggish and poorly suited for probing neural function at the rapid timescales involved in sentence comprehension. However, recent studies have shown the value of acquiring data with very short repetition times (TRs), not merely in terms of improvements in contrast to noise ratio (CNR) through averaging, but also in terms of additional fine-grained temporal information. Using multiband-accelerated fMRI, we achieved whole-brain scans at 3-mm resolution with a TR of just 500 ms at both 3T and 7T field strengths. By taking advantage of word timing information, we found that word decoding accuracy across two separate sets of scan sessions improved significantly, with better overall performance at 7T than at 3T. The effect of TR was also investigated; we found that substantial word timing information can be extracted using fast TRs, with diminishing benefits beyond TRs of 1000 ms.

Indexed as

ReadingAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleTime Factors7Tdecodingfunctional magnetic resonance imagingmultibandtimingwords

Identifiers

PMID27686111
PMCPMC5226857

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.