ArticlePloS one
Hemodynamics in Coronary Arterial Tree of Serial Stenoses.
Article in PloS one. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Fluid-Structure Interaction Analysis of Hyoid Bone-Induced Compression on Carotid Artery Hemodynamics.Biomedical engineering and computational biology · 2026Article
- Flow Characteristics by Blood Speckle Imaging in Non-Stenotic Congenital Aortic Root Disease Surrounding Valve-Preserving Operations.Bioengineering (Basel, Switzerland) · 2025Article
- Enhancing cardiac assessments: accurate and efficient prediction of quantitative fractional flow reserve.Frontiers in bioengineering and biotechnology · 2025Article
- Blood Speckle Imaging: An Emerging Method for Perioperative Evaluation of Subaortic and Aortic Valvar Repair.Bioengineering (Basel, Switzerland) · 2023Article
- Article
- Myocardial infarction impaired wall mechanics and hemodynamics in peripheral arteries.Frontiers in physiology · 2023Article
- Influence of MRI-based boundary conditions on type B aortic dissection simulations in false lumen with or without abdominal aorta involvement.Frontiers in physiology · 2022Article
- Influence of microcirculation load on FFR in coronary artery stenosis model.BMC cardiovascular disorders · 2020Article
- Vertebral Artery Stenoses Contribute to the Development of Diffuse Plaques in the Basilar Artery.Frontiers in bioengineering and biotechnology · 2020Article
- Morphometric and hemodynamic parameter dataset for coronary artery aneurysms caused by atherosclerosis.Data in brief · 2019Article
- New Mathematical Correction Model in Pursuit of Optimal Hemodynamic Assessment of Serial Coronary Artery Disease: Overcoming Hyperemic Cross Talk Between Coronary Stenoses in Series?Journal of the American Heart Association · 2018Article
- The Coronary Artery Running Pattern is One of the Causes of Individual Differences in the Progression of Coronary Atherosclerosis in WHHLMI Rabbits, an Animal Model for Coronary Atherosclerosis.Journal of atherosclerosis and thrombosis · 2018Article
- Bifurcation Asymmetry of Small Coronary Arteries in Juvenile and Adult Mice.Frontiers in physiology · 2018Article
- Hepatic Hemangiomas Alter Morphometry and Impair Hemodynamics of the Abdominal Aorta and Primary Branches From Computer Simulations.Frontiers in physiology · 2018Article
- Hemodynamics analysis of the serial stenotic coronary arteries.Biomedical engineering online · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serial segmental narrowing frequently occurs in humans, which alters coronary hemodynamics and further affects atherosclerotic progression and plaque formation. The objective of this study was to understand the distribution of hemodynamic parameters in the epicardial left main coronary arterial (LMCA) tree with serial stenoses reconstructed from patient computer tomography angiography (CTA) images. A finite volume method was used in conjunction with the inlet pressure wave and outlet flow resistance. The time-averaged wall shear stress (TAWSS) and oscillatory shear index (OSI) were determined from the flow field. A stenosis at a mother vessel mainly deteriorated the hemodynamics near the bifurcation while a stenosis at a daughter vessel affected the remote downstream bifurcation. In comparison with a single stenosis, serial stenoses increased the peak pressure gradient along the main trunk of the epicardial left anterior descending arterial tree by > 50%. An increased distance between serial stenoses further increased the peak pressure gradient. These findings have important implications on the diagnosis and treatment of serial coronary stenoses.
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Registered trials
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