Evidence map›Paper›PMID 27685652›Full record

ArticlePloS one

SparkText: Biomedical Text Mining on Big Data Framework.

Zhan Ye, Ahmad P Tafti, Karen Y He, Kai Wang, Max M He

Abstract read
In one paragraph

Article in PloS one. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Sustainable Health Informatics: Health Informaticians as Alchemists.Studies in health technology and informatics · 2019
    Article
  5. Review
  6. Article
  7. Discovering major opioid-related research themes over time: A text mining technique.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  8. Article
  9. Article
  10. Big Data Analytics for Genomic Medicine.International journal of molecular sciences · 2017
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhan YeBiomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, WI, 54449, United States of America.
Ahmad P TaftiCenter for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, WI, 54449, United States of America.
Karen Y HeDepartment of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, 44106, United States of America.
Kai WangZilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA, 90089, United States of America.
Max M HeBiomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, WI, 54449, United States of America.ORCID http://orcid.org/0000-0002-5347-6374

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
BIOMETRIC-GENETIC ANALYSIS OF CARDIOVASCULAR DISEASET32HL007567 · NHLBI · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI ZHU, XIAOFENG · 1985 to 2021
$6.0M
Integrated variation detection annotation and analysis for high-throughout sequeR01HG006465 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, KAI · 2012 to 2016
$1.8M
NCATS NIH HHS UL1 TR000427NHGRI NIH HHS R01 HG006465NHLBI NIH HHS T32 HL007567
6 · The paper itself

Abstract

backgroundMany new biomedical research articles are published every day, accumulating rich information, such as genetic variants, genes, diseases, and treatments. Rapid yet accurate text mining on large-scale scientific literature can discover novel knowledge to better understand human diseases and to improve the quality of disease diagnosis, prevention, and treatment.

resultsIn this study, we designed and developed an efficient text mining framework called SparkText on a Big Data infrastructure, which is composed of Apache Spark data streaming and machine learning methods, combined with a Cassandra NoSQL database. To demonstrate its performance for classifying cancer types, we extracted information (e.g., breast, prostate, and lung cancers) from tens of thousands of articles downloaded from PubMed, and then employed Naïve Bayes, Support Vector Machine (SVM), and Logistic Regression to build prediction models to mine the articles. The accuracy of predicting a cancer type by SVM using the 29,437 full-text articles was 93.81%. While competing text-mining tools took more than 11 hours, SparkText mined the dataset in approximately 6 minutes.

conclusionsThis study demonstrates the potential for mining large-scale scientific articles on a Big Data infrastructure, with real-time update from new articles published daily. SparkText can be extended to other areas of biomedical research.

Identifiers

PMID27685652
PMCPMC5042555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.