Evidence map›Paper›PMID 27685537›Full record

ArticleeLife2016

Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies.

Silvia Urbansky, Paula González Avalos, Maike Wosch, Steffen Lemke

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Breaking anterior-posterior symmetry in the moth flybioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Molecular biology of the cell · 2024
    Article
  6. The evolution of gastrulation morphologies.Development (Cambridge, England) · 2023
    Review
  7. Article
  8. The extended analogy of extraembryonic development in insects and amniotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  9. Evidence for a Role of the Lateral Ectoderm inFrontiers in cell and developmental biology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Silvia UrbanskyCentre for Organismal Studies Heidelberg, Heidelberg University, Heidelberg, Germany.
Paula González AvalosCentre for Organismal Studies Heidelberg, Heidelberg University, Heidelberg, Germany.
Maike WoschCentre for Organismal Studies Heidelberg, Heidelberg University, Heidelberg, Germany.
Steffen LemkeCentre for Organismal Studies Heidelberg, Heidelberg University, Heidelberg, Germany.ORCID 0000-0001-5807-2865
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrulation constitutes a fundamental yet diverse morphogenetic process of metazoan development. Modes of gastrulation range from stochastic translocation of individual cells to coordinated infolding of an epithelial sheet. How such morphogenetic differences are genetically encoded and whether they have provided specific developmental advantages is unclear. Here we identify two genes,

Indexed as

GastrulationAnimalsChironomidaeDrosophila melanogasterDrosophila ProteinsMembrane ProteinsMesodermDrosophila ProteinsFOG protein, DrosophilaMembrane ProteinsT48 protein, Drosophilacell ingressionC. ripariusdevelopmental biologyD. melanogasterevolutionary biologygastrulationgenomicsmorphogenesisstem cellstissue invagination

Identifiers

PMID27685537
PMCPMC5042651
OpenAlexW2525577720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.