Decreased effectiveness of the influenza A(H1N1)pdm09 strain in live attenuated influenza vaccines: an observational bias or a technical challenge?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial Among Preschool-Aged Children in Urban Bangladesh.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
   Trial
2. Live Attenuated Influenza Vaccination Before 3 Years of Age and Subsequent Development of Asthma: A 14-year Follow-up Study.The Pediatric infectious disease journal · 2018
   Trial
3. Live Attenuated Cold-Adapted Influenza Vaccines.Cold Spring Harbor perspectives in medicine · 2021
   Review
4. Viral Shedding in Recipients of Live Attenuated Influenza Vaccine in the 2016-2017 and 2017-2018 Influenza Seasons in the United Kingdom.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
   Article
5. Functional immune response to influenza H1N1 in children and adults after live attenuated influenza virus vaccination.Scandinavian journal of immunology · 2019
   Article
6. Influenza-associated mortality in hospital care: a retrospective cohort study of risk factors and impact of oseltamivir in an English teaching hospital, 2016 to 2017.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
   Article
7. End of season influenza vaccine effectiveness in adults and children in the United Kingdom in 2017/18.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
   Observational
8. Influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children in England in the 2015-2016 influenza season - a test-negative case-control study.Epidemiology and infection · 2019
   Article
9. Burden, effectiveness and safety of influenza vaccines in elderly, paediatric and pregnant populations.Therapeutic advances in vaccines and immunotherapy · 2019
   Review
10. Two Live Attenuated Vaccines against Recent Low⁻and Highly Pathogenic H7N9 Influenza Viruses Are Safe and Immunogenic in Ferrets.Vaccines · 2018
    Article
11. IgA polymerization contributes to efficient virus neutralization on human upper respiratory mucosa after intranasal inactivated influenza vaccine administration.Human vaccines & immunotherapeutics · 2018
    Article
12. Uptake and impact of vaccinating primary school-age children against influenza: experiences of a live attenuated influenza vaccine programme, England, 2015/16.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
13. Perspectives from the Society for Pediatric Research: Decreased Effectiveness of the Live Attenuated Influenza Vaccine.Pediatric research · 2018
    Review
14. End-of-season influenza vaccine effectiveness in adults and children, United Kingdom, 2016/17.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017
    Article
15. Live attenuated influenza vaccine effectiveness against hospitalisation due to laboratory-confirmed influenza in children two to six years of age in England in the 2015/16 season.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017
    Article
16. Letter to the editor: Potential causes of the decreased effectiveness of the influenza A(H1N1)pdm09 strain in live attenuated influenza vaccines.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016
    Article
17. Letter to the editor: Regarding the editorial by Penttinen and Friede.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016
    Article
18. Author's reply: Regarding the editorial by Penttinen and Friede.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016
    Article

Corrections and comments

• Commented on by
  Letter to the editor: Regarding the editorial by Penttinen and Friede.2016
• Commented on by
  Author's reply: Regarding the editorial by Penttinen and Friede.2016
• Erratum issued
  Authors' correction for Euro Surveill. 2016;21(38).2016

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as