Evidence map›Paper›PMID 27684419›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2017

Prospective economic evaluation alongside the non-invasive ventilation trial.

M E Mowitz, J A F Zupancic, D Millar, H Kirpalani, J S Gaulton, R S Roberts, W Mao, D Dukhovny

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Length of stay and cost of birth hospitalization: effects of subfertility and ART.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Article
  10. [Research advances in neonatal nasal intermittent positive pressure ventilation].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M E MowitzDepartment of Pediatrics, Division of Neonatology, University of Florida, Gainesville, FL, USA.
J A F ZupancicDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
D MillarRoyal Maternity Hospital, Belfast, UK.
H KirpalaniThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
J S GaultonBoston Children's Hospital, Boston, MA, USA.
R S RobertsThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
W MaoDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
D DukhovnyDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Funding

UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
CIHR MCT-80246NCATS NIH HHS UL1 TR000064
6 · The paper itself

Abstract

objectiveTo determine the cost-effectiveness of nasal continuous positive pressure (nCPAP) compared with nasal intermittent positive pressure ventilation (NIPPV) in the context of the reported randomized clinical trial. STUDY

designUsing patient-level data from the clinical trial, we undertook a prospectively planned economic evaluation. We measured costs, from a third-party payer perspective in all patients, and from a societal perspective in a subgroup with a time horizon through the earlier of discharge, death or 44 weeks post-menstrual age.

resultsFrom the third-party payer perspective, the mean cost of hospitalization per infant was statistically similar, $143 745 in the NIPPV group compared to $140 403 in the nCPAP group. Cost-effectiveness evaluation revealed a 61% probability that NIPPV is more expensive and less effective than nCPAP. Similar results were found in subgroup analysis from a societal perspective.

conclusionIn addition to being clinically equivalent, economic evaluation confirms that NIPPV, as employed in this trial, is also not economically favorable.

Indexed as

Continuous Positive Airway PressureCost-Benefit AnalysisFemaleGestational AgeHealth Care CostsHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalIntermittent Positive-Pressure VentilationMaleNoninvasive VentilationProspective StudiesRespiratory Distress Syndrome, NewbornSensitivity and Specificity

Identifiers

PMID27684419
PMCPMC6955038

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.