SynthesisJournal of clinical gastroenterology2017
The Effect of Right Colon Retroflexion on Adenoma Detection: A Systematic Review and Meta-analysis.
Synthesis in Journal of clinical gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03735953 (Retroflexion in the Entire Colon for the Detection of Colon-related Diseases), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Retroflexion in the Entire Colon for the Detection of Colon-related Diseases
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024Guideline
- Efficacy of colonoscopic re-examination across the entire colon: a randomized controlled trial.Surgical endoscopy · 2024Trial
- Impact of second forward-view examination on adenoma detection rate during unsedated colonoscopy: a randomized controlled trial.BMC gastroenterology · 2021Trial
- Proximal retroflexion versus second forward view of the right colon during screening colonoscopy: A multicentre randomized controlled trial.United European gastroenterology journal · 2020Trial
- Retrograde inspectionWorld journal of gastroenterology · 2020Trial
- Trial
- Clinical value of rectal retroflexion during colonoscopy: a retrospective analysis.BMC gastroenterology · 2026Article
- Management of Large Non-Pedunculated Polyps of the Colon: Practice-Oriented Answers to Clinical Questions.Journal of clinical medicine · 2026Review
- Colonoscopy Quality Indicators in Transition: From Adenoma Detection Rate to Serrated Lesion Detection and Beyond.Diagnostics (Basel, Switzerland) · 2026Review
- Optimizing detection and resection of colorectal polyps.Translational gastroenterology and hepatology · 2026Review
- Combating Post-colonoscopy Colorectal Cancer: Insight from the Trials and Cohort Studies.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024Article
- Risk Factors Related to Polyp Miss Rate of Short-Term Repeated Colonoscopy.Digestive diseases and sciences · 2023Article
- The Role of an Artificial Intelligence Method of Improving the Diagnosis of Neoplasms by Colonoscopy.Diagnostics (Basel, Switzerland) · 2023Article
- Second exam of right colon improves adenoma detection rate: Systematic review and meta-analysis of randomized controlled trials.Endoscopy international open · 2022Review
- Artificial Intelligence for Colonoscopy: Past, Present, and Future.IEEE journal of biomedical and health informatics · 2022Article
- Establishment and evaluation of a nomogram predicting risks of missed diagnoses of colorectal polyps.BMC gastroenterology · 2022Article
- Impact of Fellow Participation During Colonoscopy on Adenoma Detection Rates.Digestive diseases and sciences · 2022Article
- Serrated lesions: A challenging enemy.World journal of gastroenterology · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAlthough colonoscopy with polypectomy can prevent up to 80% of colorectal cancers, a significant adenoma miss rate still exists, particularly in the right colon. Previous studies addressing right colon retroflexion have revealed discordant evidence regarding the benefit of this maneuver on adenoma detection with concomitant concerns about safety and rates of maneuver success. In this meta-analysis, we sought to determine the effect of right colon retroflexion on improving adenoma detection compared with conventional colonoscopy without retroflexion, as well as determine the rates of retroflexion maneuver success and adverse events.
methodsMultiple databases including MEDLINE, Embase, and Web of Science were searched for studies on right colon retroflexion and its impact on adenoma detection compared with conventional colonoscopy. Pooled analyses of adenoma detection and retroflexion success were based on mixed-effects and random-effects models with heterogeneity analyses.
resultsEight studies met the inclusion criteria (N=3660). The primary analysis comparing colonoscopy with right-sided retroflexion versus conventional colonoscopy to determine the per-adenoma miss rate in the right colon was 16.9% (95% confidence interval, 12.5%-22.5%). The overall rate of successful retroflexion was 91.9% (95% confidence interval, 86%-95%) and rate of adverse events was 0.03%.
conclusionsColonoscopy with right-sided retroflexion significantly increases the detection of adenomas in the right colon compared with conventional colonoscopy with a high rate of maneuver success and small risk of adverse events. Thus, reexamination of the right colon in retroflexed view should be strongly considered in future standard of care colonoscopy guidelines for quality improvement in colon cancer prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.