Evidence map›Paper›PMID 27683878›Full record

ArticleASN neuro2016

Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice.

Joshua D Aaker, Benayahu Elbaz, Yuwen Wu, Timothy J Looney, Li Zhang, Bruce T Lahn, Brian Popko

Open access · goldAbstract read
In one paragraph

Article in ASN neuro, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Article
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  6. Article
  7. mNeuron · 2020
    Article
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joshua D AakerDepartment of Neurology, The University of Chicago Center for Peripheral Neuropathy, The University of Chicago, IL, USA.
Benayahu ElbazDepartment of Neurology, The University of Chicago Center for Peripheral Neuropathy, The University of Chicago, IL, USA.
Yuwen WuDepartment of Neurology, The University of Chicago Center for Peripheral Neuropathy, The University of Chicago, IL, USA.
Timothy J LooneyDepartment of Human Genetics, The University of Chicago, IL, USA.
Li ZhangDepartment of Human Genetics, The University of Chicago, IL, USA.
Bruce T LahnDepartment of Human Genetics, The University of Chicago, IL, USA.
Brian PopkoDepartment of Neurology, The University of Chicago Center for Peripheral Neuropathy, The University of Chicago, IL, USA bpopko@neurology.bsd.uchicago.edu.
University of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transcription factor, zinc finger protein 191 (ZFP191), results in oligodendrocyte development abnormalities and CNS hypomyelination. Using a previously described mutant mouse that is deficient in ZFP191 protein expression (Zfp191

Indexed as

cholesterol biosynthesishypomyelinationoligodendrocyte developmentshiverertranscriptional networksZFP191

Identifiers

PMID27683878
PMCPMC5046175
OpenAlexW2525481091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.