Evidence map›Paper›PMID 27683674›Full record

ReviewJournal of spine surgery (Hong Kong)2015

Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF.

Ralph J Mobbs, Kevin Phan, Greg Malham, Kevin Seex, Prashanth J Rao

5 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of spine surgery (Hong Kong), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 713 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
713citing papers in PubMed, 10 pooled it
29.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03877341 nacompletednot on this mapstarted 2019, after this paper: background citation

Sagittal Parameters After Mono Segmental Lumber Fusion: Interbody Versus Postrolateral Fusion

TypeinterventionalSponsorAssiut UniversityRan2019 to 2023Enrolled42ConditionsLumbar Spine FusionArmsposterolateral fusion, posterior lumbar interbody fusion
NCT05565456 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Prospective Hounsfield Unit Measurements of Intercorporal Bone Grafts Remodelling Towards Spinal Fusion

TypeobservationalSponsorRijnstate HospitalRan2022 to 2026Enrolled30ConditionsSpondylolisthesis, Spinal Fusion
NCT06367855 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF

TypeinterventionalSponsorPotsawat SurabotsoponRan2024 to 2025Enrolled60ConditionsSpinal Stenosis Lumbar, Disc Degeneration, Disc Disease, Fusion of SpineArmsDexamethasone, Normal saline
NCT06989632 completednot on this map

Total Lumbar Disc Prosthesis and Subsequent Work Activity 5 Years After Total Lumbar Disc Replacement

TypeobservationalSponsorUniversity of ValenciaRan2008 to 2025Enrolled130ConditionsLumbar Disc Degeneration, Lumbar Disc Disease, Sciatica, Lumbar Disc HerniationArmsTotal lumbar disc prosthesis (Baguera®L, Spineart, Switzerland)
NCT07127380 narecruitingnot on this mapstarted 2025, after this paper: background citation

MID-MIS Trail Protocol - Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain

TypeinterventionalSponsorCopernicus Memorial HospitalRan2025 to 2028Enrolled100ConditionsLower Back Pain Chronic, Lumbar Degenerative Disease, Lumbar Disc Degeneration, Degenerative Disc Disease(DDD)ArmsMidline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF)
3 · Its place in the literature

Who cites it

713 citing papers in PubMed, 10 syntheses or guidelines pooled it, 1,300 citations in OpenAlex.

  1. Pooled it
  2. The Added Value and the Efficacy of Preoperative Physiotherapy on Degenerative Diseases of the Lumbar Spine: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Pooled it
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  9. Evaluating the prognostic role of computed tomography Hounsfield units in anticipating spinal outcomes post-instrumentation: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  10. Morselized corticocancellous bone as primary graft for posterior lumbar fusion: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  11. Trial
  12. Article
  13. Article
  14. Abdominal aortic calcification and functional recovery in patients undergoing posterior lumbar interbody fusion: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  15. Article
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  18. Impact of adjunctive spine surgery on multilevel spinal fusion in the management of adult spinal deformity: A single centre propensity score-matched analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  19. Observational
  20. A decade of impact: theJournal of spine surgery (Hong Kong) · 2026
    Article

653 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ralph J MobbsNeuroSpine Surgery Research Group (NSURG), Sydney, Australia;; Prince of Wales Private Hospital, Randwick, Sydney, Australia;; University of New South Wales (UNSW), Sydney, Australia;
Kevin PhanNeuroSpine Surgery Research Group (NSURG), Sydney, Australia;; Prince of Wales Private Hospital, Randwick, Sydney, Australia;; University of New South Wales (UNSW), Sydney, Australia;
Greg MalhamNeuroscience Institute, Epworth Hospital, Richmond VIC, Australia ;
Kevin SeexNeurosurgery Department, Macquarie University, Sydney, Australia.
Prashanth J RaoNeuroSpine Surgery Research Group (NSURG), Sydney, Australia;; Prince of Wales Private Hospital, Randwick, Sydney, Australia;; University of New South Wales (UNSW), Sydney, Australia;
Prince of Wales Hospital · AUEpworth Hospital · AUMacquarie University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative disc and facet joint disease of the lumbar spine is common in the ageing population, and is one of the most frequent causes of disability. Lumbar spondylosis may result in mechanical back pain, radicular and claudicant symptoms, reduced mobility and poor quality of life. Surgical interbody fusion of degenerative levels is an effective treatment option to stabilize the painful motion segment, and may provide indirect decompression of the neural elements, restore lordosis and correct deformity. The surgical options for interbody fusion of the lumbar spine include: posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), minimally invasive transforaminal lumbar interbody fusion (MI-TLIF), oblique lumbar interbody fusion/anterior to psoas (OLIF/ATP), lateral lumbar interbody fusion (LLIF) and anterior lumbar interbody fusion (ALIF). The indications may include: discogenic/facetogenic low back pain, neurogenic claudication, radiculopathy due to foraminal stenosis, lumbar degenerative spinal deformity including symptomatic spondylolisthesis and degenerative scoliosis. In general, traditional posterior approaches are frequently used with acceptable fusion rates and low complication rates, however they are limited by thecal sac and nerve root retraction, along with iatrogenic injury to the paraspinal musculature and disruption of the posterior tension band. Minimally invasive (MIS) posterior approaches have evolved in an attempt to reduce approach related complications. Anterior approaches avoid the spinal canal, cauda equina and nerve roots, however have issues with approach related abdominal and vascular complications. In addition, lateral and OLIF techniques have potential risks to the lumbar plexus and psoas muscle. The present study aims firstly to comprehensively review the available literature and evidence for different lumbar interbody fusion (LIF) techniques. Secondly, we propose a set of recommendations and guidelines for the indications for interbody fusion options. Thirdly, this article provides a description of each approach, and illustrates the potential benefits and disadvantages of each technique with reference to indication and spine level performed.

Indexed as

anterior lumbar interbody fusion (ALIF)anterior to psoas (ATP)Degenerative disc diseaseinterbodylateral lumbar interbody fusion (LLIF)lumbar spine fusionminimally invasive transforaminal lumbar interbody fusion (MI-TLIF)oblique lumbar interbody fusion (OLIF)posterior lumbar interbody fusion (PLIF)spinetransforaminal lumbar interbody fusion (TLIF)

Identifiers

PMID27683674
PMCPMC5039869
OpenAlexW2373138909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.