Evidence map›Paper›PMID 27683589›Full record

ArticleFrontiers in biology2015

Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD

Felicia Tsang, Su-Ju Lin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. NADCells · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. The Histone Deacetylases Hst1 and Rpd3 Integrate De Novo NADInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. NADFrontiers in molecular biosciences · 2021
    Review
  10. NADBiomolecules · 2020
    Review
  11. Cross-talk in NADCurrent genetics · 2019
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Felicia TsangDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, CA 95616, USA.
Su-Ju LinDepartment of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, CA 95616, USA.
University of California, Davis · US

Funding

Understanding the Regulation of NAD+Homeostasis and SignalingR01GM102297 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LIN, SU-JU · 2012 to 2019
$2.2M
NIGMS NIH HHS R01 GM102297
6 · The paper itself

Abstract

Nutrient sensing pathways and their regulation grant cells control over their metabolism and growth in response to changing nutrients. Factors that regulate nutrient sensing can also modulate longevity. Reduced activity of nutrient sensing pathways such as glucose-sensing PKA, nitrogen-sensing TOR and S6 kinase homolog Sch9 have been linked to increased life span in the yeast,

Indexed as

NAD+ homeostasisNutrient sensingyeast longevity

Identifiers

PMID27683589
PMCPMC5036586
OpenAlexW1885635670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.