Evidence map›Paper›PMID 27683454›Full record

ArticleEJIFCC2014

An Emerging Role of TEX101 Protein as a Male Infertility Biomarker.

Christina G Schiza, Keith Jarv, Eleftherios P Diamandis, Andrei P Drabovich

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in EJIFCC, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

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  7. Alleviation of carbendazim toxicity effect bySaudi journal of biological sciences · 2024
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  15. Proteins as the Molecular Markers of Male Fertility.Journal of human reproductive sciences
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christina G SchizaDepartment of Laboratory Medicine and Pathobiology, University of Toronto , Toronto, ON, Canada .
Keith JarvDepartment of Surgery (Division of Urology), Mount Sinai Hospital, University of Toronto , Toronto, ON, Canada .
Eleftherios P DiamandisDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.;
Andrei P DrabovichLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital , Toronto, ON, Canada .
University of Toronto · CAMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is an important aspect of human reproduction. It affects up to 15% of couples, with the male factor contributing to approximately 50% of all cases. Azoospermia is one of the most severe forms of male infertility, which is characterized by the absence of sperm in semen. The mechanisms underlying male infertility remain unknown. Currently, clinicians rely on semen analysis to predict the reproductive potential of a male, and testicular biopsy is the only reliable method to diagnose different subtypes of azoospermia. Recently, advances in proteomics encouraged the search for novel male infertility biomarkers in seminal plasma. In this review, we focus on TEX101, a testicular germ cell-specific protein, one of the most promising male infertility biomarkers. We discuss its role in spermatogenesis and fertilization and summarize our current knowledge about this new potential biomarker.

Indexed as

Acrosome reactionAzoospermialomarkersMale infertilitySpermSpermatogenesisTEX101

Identifiers

PMID27683454
PMCPMC4975188
OpenAlexW2559347256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.