ArticleProceedings. Biological sciences2016
Reconstructing the emergence of a lethal infectious disease of wildlife supports a key role for spread through translocations by humans.
Article in Proceedings. Biological sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 87 citations in OpenAlex.
- The final frontier: using carcasses for one health surveillance at the ecosystem interface.Frontiers in veterinary science · 2025Article
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- Cultivable Skin Mycobiota of Healthy and Diseased Blind Cave Salamander (Frontiers in microbiology · 2022Article
- Characterizing the demographic history and prion protein variation to infer susceptibility to chronic wasting disease in a naïve population of white-tailed deer (Evolutionary applications · 2021Article
- Using Hawkes Processes to model imported and local malaria cases in near-elimination settings.PLoS computational biology · 2021Article
- Long-Term Monitoring of Amphibian Populations of a National Park in Northern Spain Reveals Negative Persisting Effects ofFrontiers in veterinary science · 2021Article
- Social structure defines spatial transmission of African swine fever in wild boar.Journal of the Royal Society, Interface · 2021Article
- High pathogen prevalence in an amphibian and reptile assemblage at a site with risk factors for dispersal in Galicia, Spain.PloS one · 2020Article
- Frog Virus 3 Genomes Reveal Prevalent Recombination between Ranavirus Lineages and Their Origins in Canada.Journal of virology · 2019Article
- eDNA Increases the Detectability of Ranavirus Infection in an Alpine Amphibian Population.Viruses · 2019Article
- Water sports could contribute to the translocation of ranaviruses.Scientific reports · 2019Article
- Diversity-Stability Dynamics of the Amphibian Skin Microbiome and Susceptibility to a Lethal Viral Pathogen.Frontiers in microbiology · 2019Article
- Outbreaks of an Emerging Viral Disease Covary With Differences in the Composition of the Skin Microbiome of a Wild United Kingdom Amphibian.Frontiers in microbiology · 2019Article
- The influence of landscape and environmental factors on ranavirus epidemiology in a California amphibian assemblage.Freshwater biology · 2018Article
- Dynamic network measures reveal the impact of cattle markets and alpine summering on the risk of epidemic outbreaks in the Swiss cattle population.BMC veterinary research · 2018Article
- Article
- Are RNA Viruses Candidate Agents for the Next Global Pandemic? A Review.ILAR journal · 2017Review
- Rapid extirpation of a North American frog coincides with an increase in fungal pathogen prevalence: Historical analysis and implications for reintroduction.Ecology and evolution · 2017Article
- Screening of a long-term sample set reveals two Ranavirus lineages in British herpetofauna.PloS one · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
There have been few reconstructions of wildlife disease emergences, despite their extensive impact on biodiversity and human health. This is in large part attributable to the lack of structured and robust spatio-temporal datasets. We overcame logistical problems of obtaining suitable information by using data from a citizen science project and formulating spatio-temporal models of the spread of a wildlife pathogen (genus Ranavirus, infecting amphibians). We evaluated three main hypotheses for the rapid increase in disease reports in the UK: that outbreaks were being reported more frequently, that climate change had altered the interaction between hosts and a previously widespread pathogen, and that disease was emerging due to spatial spread of a novel pathogen. Our analysis characterized localized spread from nearby ponds, consistent with amphibian dispersal, but also revealed a highly significant trend for elevated rates of additional outbreaks in localities with higher human population density-pointing to human activities in also spreading the virus. Phylogenetic analyses of pathogen genomes support the inference of at least two independent introductions into the UK. Together these results point strongly to humans repeatedly translocating ranaviruses into the UK from other countries and between UK ponds, and therefore suggest potential control measures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.