ReviewAging2016
The role of hydrogen sulfide in aging and age-related pathologies.
Review in Aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023Pooled it
- The effects of bathing in neutral bicarbonate ion water.Scientific reports · 2021Trial
- Breath-based stratification of asthma severity using the MISTRAL platform with integrated HScientific reports · 2025Article
- Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-9.Cardiovascular drugs and therapy · 2025Article
- Cystathionine Gamma-Lyase: A Potential Longevity Gene Under Selection?Journal of molecular evolution · 2025Article
- Fecal microbiota transplant from long-living Ames dwarf mice alters the microbial composition and biomarkers of liver health in normal mice.GeroScience · 2025Article
- The Janus Face of Oxidative Stress and Hydrogen Sulfide: Insights into Neurodegenerative Disease Pathogenesis.Antioxidants (Basel, Switzerland) · 2025Review
- Role of Microbiota-Derived Hydrogen Sulfide (HBiomedicines · 2024Review
- Asynchronous changes of hydrogen sulfide and its generating enzymes in most tissues with the aging process.Bioscience reports · 2024Article
- Review
- Electrochemical Detection of Gasotransmitters: Status and Roadmap.ACS sensors · 2024Review
- Amino acid restriction, aging, and longevity: an update.Frontiers in aging · 2024Review
- Chemistry of Hydrogen Sulfide-Pathological and Physiological Functions in Mammalian Cells.Cells · 2023Review
- Ageing-Related Alterations in Renal Epithelial Glucose Transport.International journal of molecular sciences · 2023Article
- Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota.Nature metabolism · 2023Article
- Inflammation and Oxidative Stress in Frailty and Metabolic Syndromes-Two Sides of the Same Coin.Metabolites · 2023Review
- Hydrogen Sulfide Metabolizing Enzymes in the Intestinal Mucosa in Pediatric and Adult Inflammatory Bowel Disease.Antioxidants (Basel, Switzerland) · 2022Article
- Sodium Thiosulphate-Loaded Liposomes Control Hydrogen Sulphide Release and Retain Its Biological Properties in Hypoxia-like Environment.Antioxidants (Basel, Switzerland) · 2022Article
- The Potential Implications of Hydrogen Sulfide in Aging and Age-Related Diseases through the Lens of Mitohormesis.Antioxidants (Basel, Switzerland) · 2022Review
- Inhibition of the 3-mercaptopyruvate sulfurtransferase-hydrogen sulfide system promotes cellular lipid accumulation.GeroScience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When humans grow older, they experience inevitable and progressive loss of physiological function, ultimately leading to death. Research on aging largely focuses on the identification of mechanisms involved in the aging process. Several proposed aging theories were recently combined as the 'hallmarks of aging'. These hallmarks describe (patho-)physiological processes that together, when disrupted, determine the aging phenotype. Sustaining evidence shows a potential role for hydrogen sulfide (H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.