Evidence map›Paper›PMID 27682654›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2017

The association of endothelin-1 with markers of oxidative stress in a biethnic South African cohort: the SABPA study.

Christine Susara du Plooy, Catharina Martha Cornelia Mels, Hugo Willem Huisman, Ruan Kruger

Abstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. The Impact ofAntioxidants (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Review
  8. Oxidative Stress: A Unifying Paradigm in Hypertension.The Canadian journal of cardiology · 2020
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christine Susara du PlooyHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
Catharina Martha Cornelia MelsHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
Hugo Willem HuismanHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
Ruan KrugerHypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
North-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both endothelin-1 and oxidative stress have important roles in the development of cardiovascular diseases such as hypertension and atherosclerosis. Limited information is available on the interaction between oxidative stress, the glutathione system and endothelin-1 in humans. We aimed to investigate the association of endothelin-1 with markers of oxidative stress and the antioxidant capacity in a biethnic South African cohort. This cross-sectional study included 195 black and 198 white South Africans. Serum endothelin-1 levels and oxidative stress-related markers such as reactive oxygen species (measured as serum peroxides), glutathione peroxidase, glutathione reductase, superoxide dismutase and catalase were measured. In single, partial and multiple regression analyses endothelin-1 correlated positively with glutathione reductase activity (adj. R

Indexed as

AdultBiomarkersBlack PeopleBlood PressureCatalaseCholesterolCross-Sectional StudiesEndothelin-1FemaleGlutathione PeroxidaseGlutathione ReductaseHumansMaleMiddle AgedOxidative StressReactive Oxygen SpeciesBiomarkersCatalaseCholesterolEndothelin-1Glutathione PeroxidaseGlutathione ReductaseReactive Oxygen SpeciesSuperoxide Dismutase

Identifiers

PMID27682654
OpenAlexW2526883093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.